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Medical Radiation Therapy Systems sector

Strategic acquirers, private equity (buyout funds and growth funds) firms, and valuation benchmarks for Medical Radiation Therapy Systems

1.1 - About Medical Radiation Therapy Systems sector

Companies in Medical Radiation Therapy Systems design and manufacture devices and software used to deliver therapeutic radiation to cancer patients. Offerings span external beam and internal radiation modalities, combining precise dose delivery with imaging, planning, and workflow tools. Strategic buyers in this category focus on clinical efficacy, safety, and operational reliability, enabling providers to treat more cases, personalize therapy, and maintain compliance across complex oncology service lines.

Typical capabilities include linear accelerators with image‑guided and intensity‑modulated delivery, proton therapy gantries, stereotactic radiosurgery and SBRT options, and brachytherapy systems. Vendors pair these with treatment planning algorithms, adaptive therapy software, cone‑beam CT and MRI integration, immobilization solutions, and end‑to‑end dosimetry and QA platforms. Many provide oncology information systems, interoperability with EMR/RIS/PACS, remote system monitoring, and professional services for commissioning, calibration, and regulatory documentation.

Primary customers include hospital radiation oncology departments, comprehensive cancer centers, and outpatient radiotherapy clinics. Outcomes delivered include higher precision and tumor control, reduced treatment times and toxicity through image guidance and adaptive planning, improved throughput via streamlined workflows, and stronger compliance with dosing and safety standards. Solutions also support data integration for multidisciplinary care and better asset utilization across multi‑site health systems.

2. Buyers in the Medical Radiation Therapy Systems sector

2.1 Top strategic acquirers of Medical Radiation Therapy Systems companies

RefleXion Logo

RefleXion

HQ: United States Website
  • Description: Provider of biology-guided radiotherapy technology that fuses PET imaging with stereotactic radiotherapy, using tumors’ own emissions to steer precise, real-time radiation for localized and metastatic cancer while reducing exposure to healthy tissue.
  • Key Products:
  • Biology-Guided Radiotherapy (BgRT) Machine: Radiotherapy system that uses tumors’ PET emissions for real-time guidance, delivering accurate doses to moving targets while minimizing radiation to healthy tissue
  • PET-Radiotherapy Localization Platform: Integrates PET imaging with stereotactic radiotherapy to localize, track and treat multiple tumors simultaneously in one session, reducing margins and motion-related inaccuracies.
  • Company type: Private company
  • Employees: ●●●●●
  • Total funding raised: $●●●m
  • Backers: ●●●●●●●●●●
  • Acquisitions: ●●
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2.2 - Strategic buyer groups for Medical Radiation Therapy Systems sector

M&A buyer group 1: Oncology Informatics

11 companies View group β†’
Description: Companies in the Enterprise Oncology Informatics Platforms category provide software that consolidates clinical, pathology, imaging, and genomic data to support cancer-care workflows. These vendors deliver structured data capture, decision support, tumor registry reporting, and outcomes analytics that integrate with EHRs. The value proposition is reliable, interoperable oncology data and workflow automation that improve care coordination, quality reporting, research readiness, and operational efficiency.
Tempus

Tempus

Website β€’ HQ: United States
  • Type: N/A
  • Employees: ●●●●●
  • Description: Provider of data-driven precision medicine solutions, including genomic profiling, pharmacogenomic testing, AI-powered imaging analytics and interoperable clinical integrations that deliver actionable insights for clinicians to improve diagnosis, treatment selection and research collaboration across oncology, cardiovascular disease and other conditions.
  • Key Products:
  • Analytical Machine Learning Platform: AI-driven system that analyzes expansive clinical and molecular data in real time, enabling physicians to choose personalized therapies based on actionable insights during patient care
  • Tempus Next: Care pathway intelligence platform that identifies biomarker testing gaps, supports guideline-directed decisions, and helps oncologists deliver appropriate breast cancer treatments using integrated data analytics
  • Tempus One Clinical Assistant: On-demand digital tool that streamlines complex clinical and genomic data, giving providers rapid, clear patient insights while reducing workflow burden through AI-enabled automation
  • Fixed PDO Panels: Preclinical oncology R&D panels allowing researchers to test drug candidatesβ€”including small molecules, mAbs
  • ADCs, cell and bispecific therapiesβ€”on patient-derived organoids to assess efficacy across modalities
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Buyer group 2: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

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Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 3: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

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Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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3. Investors and private equity firms in Medical Radiation Therapy Systems sector

3.1 - Buyout funds in the Medical Radiation Therapy Systems sector

Buyout Funds investing in Medical Radiation Therapy Systems companies

51+ funds
Description: Buyout funds focused on Medical Radiation Therapy Systems companies globally.

TPG

Website β€’ HQ: United States
  • Type: Buyout
  • Fund Size: $●●●m
  • Investment Range: $●●-●●●m
  • Focus: Technology companies in Medical Radiation Therapy Systems
  • Relevant M&A transactions / similar portfolio companies:
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2.2 - Strategic buyer groups for Medical Radiation Therapy Systems sector

Growth Equity Funds in Medical Radiation Therapy Systems companies

41+ funds
Description: Growth equity funds focused on Medical Radiation Therapy Systems companies globally.

Summit Partners

Website β€’ HQ: United States
  • Type: Growth
  • Fund Size: $●●●m
  • Investment Range: $●●-●●●m
  • Focus: High-growth companies in Medical Radiation Therapy Systems
  • Relevant investments / similar portfolio companies:
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4 - Top valuation comps for Medical Radiation Therapy Systems companies

4.2 - Public trading comparable groups for Medical Radiation Therapy Systems sector

Description: Companies in this public trading comparables group deliver diagnostic imaging devices, contrast agents, and provider-based imaging and laboratory services. Business models span capital equipment sales, consumables, and fee-for-service testing with payer reimbursement. They are comparable because revenues are driven by procedure volumes, installed base penetration, clinical accuracy, and referral networks, creating recurring utilization and consumables demand, with similar regulatory, compliance, and reimbursement dynamics across imaging and diagnostics end markets.
RadNet logo

RadNet

  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of diagnostic imaging services and information technology solutions, operating a network of outpatient imaging centers offering services including MRI, CT, PET/CT, X-ray, ultrasound, and mammography to enhance patient care and medical imaging infrastructure.
  • Key Products:
  • MRI: High-resolution magnetic resonance imaging services for detailed internal body scans
  • CT: Computed tomography scans for cross-sectional imaging
  • PET/CT: Positron emission tomography combined with CT for comprehensive imaging
  • X-ray: Basic and advanced X-ray imaging services for diagnostic purposes
  • Mammography: Advanced breast imaging services including digital and 3D mammography.
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Revenue growth
Median
15.7%
2025E
16.0%
2026E
EBITDA margin
Median
28.2%
2025E
28.6%
2026E
Cash EBITDA margin
Median
27.6%
2025E
28.0%
2026E
EV/Revenue
Median
8.4x
2025E
6.8x
2026E
EV/EBITDA
Median
28.9x
2025E
24.4x
2026E
EV/Cash EBITDA
Median
29.0x
2025E
25.5x
2026E
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4.3 - M&A Transactions in the Medical Radiation Therapy Systems sector

Selected M&A transactions

Date Target Description Buyer(s) Relevance EV EV/Revenue EV/EBITDA
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Frequently Asked Questions

Buyers & Acquirers in Medical Radiation Therapy Systems sector

Who are the top strategic acquirers of Medical Radiation Therapy Systems companies?

Top strategic buyers in this sector include RefleXion, a provider of biology-guided radiotherapy technology that fuses pet imaging with stereotactic radiotherapy, using tumors’ own emissions to steer precise, real-time radiation for localized and metastatic cancer while reducing exposure to healthy tissue. .

Which buyer groups are most relevant for Medical Radiation Therapy Systems companies?

Relevant strategic buyer groups similar to the Medical Radiation Therapy Systems sector include Oncology Informatics because they share similar customer segments and product capabilities.

Financial Investors in Medical Radiation Therapy Systems sector

Which are the top PE firms investing in Medical Radiation Therapy Systems companies?

Potential investors in the broader Medical Radiation Therapy Systems space include Summit Partners and TPG.

Who are the top buyout funds acquiring Medical Radiation Therapy Systems companies?

Active PE funds and buyout funds acquiring companies in the Medical Radiation Therapy Systems space include TPG.

Who are the top growth equity funds investing in Medical Radiation Therapy Systems companies?

Growth funds investing in the broader Medical Radiation Therapy Systems sector include Summit Partners.

Valuation of Companies in Medical Radiation Therapy Systems sector

Which are the key public companies that are relevant trading comps for Medical Radiation Therapy Systems companies?

Key trading comparable groups include RadNet, a provider of diagnostic imaging services and information technology solutions, operating a network of outpatient imaging centers offering services including mri, ct, pet/ct, x-ray, ultrasound, and mammography to enhance patient care and medical imaging infrastructure..

Which are the key trading comparable groups for Medical Radiation Therapy Systems companies?

Similar trading comparable companies include Diagnostic Imaging and Clinical Diagnostics Companies. Our platform tracks detailed trading comparable groups in the Medical Radiation Therapy Systems sector with complete valuation multiples, growth metrics, and profitability data. Access the full database to benchmark your company against relevant public comparables.

What are recent M&A transactions in the Medical Radiation Therapy Systems sector?

Our platform tracks M&A transactions in the Medical Radiation Therapy Systems sector with complete deal terms, valuation multiples, and strategic rationale. Access the full database to benchmark pricing and identify active acquirers.

What are recent capital raises and funding rounds in Medical Radiation Therapy Systems?

Access recent funding rounds in the Medical Radiation Therapy Systems sector including growth equity, venture capital, and buyout investments. Our database includes round size, lead investors, valuations, and use of proceeds.

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