Company profile: Dice Therapeutics
1.1 - Company Overview
Company description
- Provider of oral small-molecule therapeutics for chronic autoimmune, inflammatory, and other diseases, leveraging a proprietary platform to build a pipeline targeting well-validated immunology pathways. Programs include IL-17 inhibitors (DC-806, DC-853) and novel scaffolds, oral α4β7 for IBD, oral αVβ1/αVβ6 for fibrotic diseases including idiopathic pulmonary fibrosis, and oral PD-L1 inhibitors for cancers.
Products and services
- DC-806: Engineered as an oral small molecule IL-17 inhibitor, it treats psoriasis and other autoimmune diseases by blocking the IL-17 pathway
- Oral α4β7 program: Developed as oral small molecule inhibitors targeting α4β7, these candidates address inflammatory bowel disease by antagonizing the α4β7 pathway
- DC-853: Built as a small molecule IL-17 inhibitor with potentially improved metabolic-stability, it aims to treat autoimmune diseases by inhibiting the IL-17 target
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Dice Therapeutics
Xcovery
HQ: United States
Website
- Description: Provider of low-toxicity, molecular-targeted oral cancer therapeutics, including Ensartinib for ALK-positive non-small cell lung cancer and Vorolanib, a VEGFR/PDGFR tyrosine kinase inhibitor for solid tumors such as renal cell carcinoma. Conducts clinical trials, seeks partnerships to launch Ensartinib globally and advance Vorolanib in combination therapy, and offers patient information and support resources.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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Circle Pharma
HQ: United States
Website
- Description: Provider of bioavailable macrocyclic peptide therapeutics targeting intracellular protein-protein interactions, supported by the MXMO platform that combines computational structure-based design and synthetic chemistry to create cell-permeable macrocycles. Offers cyclin A/B inhibitors for cancers with Retinoblastoma pathway mutations and other tumors, advancing precision oncology and therapeutics for 'undruggable' targets.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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Antigen Express
HQ: United States
Website
- Description: Provider of proprietary vaccine formulation platform and products addressing large unmet medical needs by focusing on stimulation of critical T helper cells. The technology enables antigen-specific stimulation or suppression of T-helper responses to virtually any antigen.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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Pionyr
HQ: United States
Website
- Description: Provider of immuno-oncology therapeutics that enhance antitumor immunity by targeting the tumor microenvironment. Utilizes novel target discovery and antibody generation platforms and its Myeloid Tuning approach. Programs include PY314 (TREM2) to deplete tumor-associated macrophages, PY159 (TREM1) to repolarize them to counteract immunosuppression, and PY265 (MARCO) to activate immune responses.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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Gradalis
HQ: United States
Website
- Description: Provider of personalized cancer immunotherapy leveraging patients' own genetically modified tumor cells to enhance immune recognition and killing through its Vigil platform, and of clinical trials evaluating the safety and efficacy of Vigil across cancer types, including ovarian cancer and Ewingās sarcoma.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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2.M&A buyers
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2.2 - Strategic buyer groups for Dice Therapeutics
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3. Investors and private equity firms
3.1 - Buyout funds investing in similar companies to Dice Therapeutics
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4 - Top valuation comps for Dice Therapeutics
4.2 - Public trading comparable groups for Dice Therapeutics
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