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Company profile: Inspirna

1.1 - Company Overview

Inspirna Logo

Inspirna

Headquarter: United States
Founded: 20XX🔒
Employees: 100-500🔒

Company description

  • Provider of oncology therapeutics and discovery technology, including ompenaclid (RGX-202), an oral SLC6A8 inhibitor in Phase 2 for advanced RAS-mutant colorectal cancer; abequolixron (RGX-104), an oral LXR/APOE activator in Phase 1b/2 for advanced non-small cell lung and endometrial cancer; the RNA-DRIVEr platform for novel cancer drivers; and RGX-019, a preclinical MERTK-targeting ADC; with active clinical trial recruitment.

Products and services

  • Abequolixron (RGX-104): An oral small molecule activator of LXR/APOE that blocks tumor angiogenesis and suppresses myeloid cells, enhancing anti-tumor immunity, in Phase 1b/2 for advanced NSCLC and endometrial cancer
  • Ompenaclid (RGX-202): An oral small molecule inhibitor of SLC6A8 that induces apoptosis in colorectal cancer cells, currently in Phase 2 trials for advanced colorectal cancer with RAS mutations
  • RNA-DRIVEr Discovery Platform: A proprietary discovery platform that enables identification of previously unknown cancer drivers amenable to targeting by small molecules and biologics, accelerating development of therapeutics

Key contacts

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Financial details

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1.2 - Competitors and similar companies to Inspirna

Oxford Biomedica Logo

Oxford Biomedica

HQ: United Kingdom Website
  • Description: Provider of gene and cell therapy solutions, offering lentiviral LentiVector and AAV platforms for development and manufacturing of gene therapies, plus CDMO services for viral vectors including tech transferred-in execution of client-defined methods, process development, GMP manufacturing, and regulatory support.
  • Rationale: This competitor operates in a highly similar market segment with overlapping features.
  • Company type: Private company
  • Employees: ●●●●●
  • Total funding raised: $●●●m
  • Backers: ●●●●●●●●●●
  • Acquisitions: ●●
View full Oxford Biomedica company profile →
Avivia Logo

Avivia

HQ: The Netherlands Website
  • Description: Provider of pharmaceutical CRO services, including analytical testing, drug formulation, generic drugs, repurposing, and troubleshooting.
  • Rationale: This competitor operates in a highly similar market segment with overlapping features.
  • Company type: Private company
  • Employees: ●●●●●
  • Total funding raised: $●●●m
  • Backers: ●●●●●●●●●●
  • Acquisitions: ●●
View full Avivia company profile →
Lilly Logo

Lilly

HQ: United States Website
  • Description: Provider of medicines for diabetes, cancer, immunology, and other major health areas, including insulin products with affordability initiatives ($35 or less/month); Efsitora for type 2 diabetes via autoinjector; EBGLYSS for moderate-to-severe atopic dermatitis; Jaypirca for relapsed/refractory MCL and CLL/SLL; Zepbound (tirzepatide) for obesity; Verzenio for HR+, HER2- early breast cancer.
  • Rationale: This competitor operates in a highly similar market segment with overlapping features.
  • Company type: Private company
  • Employees: ●●●●●
  • Total funding raised: $●●●m
  • Backers: ●●●●●●●●●●
  • Acquisitions: ●●
View full Lilly company profile →
Roquefort Therapeutics Logo

Roquefort Therapeutics

HQ: United Kingdom Website
  • Description: Provider of pre-clinical anti-cancer therapeutics, including Midkine-targeting antibodies; antisense oligonucleotides to reduce Midkine in cancer cells; gene-editing RNA and mRNA therapies for solid tumors; STAT-6 siRNA therapeutics; and MK cell therapy with direct and NK cell-mediated action, advancing candidates toward clinical trials.
  • Rationale: This competitor operates in a highly similar market segment with overlapping features.
  • Company type: Private company
  • Employees: ●●●●●
  • Total funding raised: $●●●m
  • Backers: ●●●●●●●●●●
  • Acquisitions: ●●
View full Roquefort Therapeutics company profile →
Confo Therapeutics Logo

Confo Therapeutics

HQ: Belgium Website
  • Description: Provider of GPCR-focused drug discovery solutions leveraging proprietary Confo® Technology and conformationally selective VHH ConfoBodies® to stabilize GPCRs in active, disease-relevant states. Offerings include ConfoScreen®, ConfoSensor®, and ConfoStructure™ for screening, biosensing, and structure-based design, and MegaBody™ for high-resolution cryo-EM, enabling novel medicine discovery and internal programs addressing unmet medical need.
  • Rationale: This competitor operates in a highly similar market segment with overlapping features.
  • Company type: Private company
  • Employees: ●●●●●
  • Total funding raised: $●●●m
  • Backers: ●●●●●●●●●●
  • Acquisitions: ●●
View full Confo Therapeutics company profile →
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2.M&A buyers

2.1 Potential strategic acquirers in the sector

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2.2 - Strategic buyer groups for Inspirna

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Buyer group 1: ████████ ████████

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Buyer group 2: ████████ ████████

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Buyer group 3: ████████ ████████

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3. Investors and private equity firms

3.1 - Buyout funds investing in similar companies to Inspirna

2.2 - Growth funds investing in similar companies to Inspirna

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4 - Top valuation comps for Inspirna

4.2 - Public trading comparable groups for Inspirna

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4.3 - M&A Transactions similar to Inspirna

Selected M&A transactions

Date Target Description Buyer(s) Relevance EV EV/Revenue EV/EBITDA
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Frequently Asked Questions

About Inspirna

What does Inspirna do?

Inspirna is a provider of oncology therapeutics and discovery technology, including ompenaclid (RGX-202), an oral SLC6A8 inhibitor in Phase 2 for advanced RAS-mutant colorectal cancer; abequolixron (RGX-104), an oral LXR/APOE activator in Phase 1b/2 for advanced non-small cell lung and endometrial cancer; the RNA-DRIVEr platform for novel cancer drivers; and RGX-019, a preclinical MERTK-targeting ADC; with active clinical trial recruitment.

Who are Inspirna's competitors?

Inspirna's competitors and similar companies include Oxford Biomedica, Avivia, Lilly, Roquefort Therapeutics, and Confo Therapeutics.

Where is Inspirna headquartered?

Inspirna is headquartered in United States.

How many employees does Inspirna have?

Inspirna has 1,000 employees 🔒.

When was Inspirna founded?

Inspirna was founded in 2010 🔒.

What sector and industry vertical is Inspirna in?

Inspirna is in the Enterprise Software 🔒 sector and industry

M&A Buyers & Acquirers for Inspirna

Who are the top strategic acquirers in Inspirna's sector and industry

Top strategic M&A buyers and acquirers in Inspirna's sector include ████████, ██████████, ██████, ████████, and ██████████ 🔒.

Which M&A buyer groups are most relevant for Inspirna?

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Financial Investors investing in Inspirna's sector and industry vertical

Which are the top PE firms investing in Inspirna's sector and industry vertical?

Top PE firms investing in Inspirna's sector and industry vertical include ████████, ██████████, ████████, and ██████████ 🔒.

Who are the top buyout funds acquiring in Inspirna's sector and industry vertical?

Active PE funds and buyout funds acquiring companies in Inspirna's sector and industry vertical include █████████, ██████████, ████████████, and ████████████ 🔒.

Who are the top growth equity funds investing in companies in Inspirna's sector and industry vertical?

Growth funds and venture capital funds investing in companies similar to Inspirna include █████████, ██████████, ████████████, and ████████████ 🔒.

Valuation benchmarks of companies in Inspirna's sector and industry

Which are the key public companies that are relevant trading comps benchmarks for Inspirna?

The key public trading comparables and valuation benchmarks for Inspirna include █████████, ██████████, ████████████, and ████████████ 🔒.

Which are the key trading comparable groups for Inspirna for public valuation benchmarks?

Our platform tracks detailed public trading comparable groups and valuation benchmarks for Inspirna with complete valuation multiples, growth metrics, and profitability data. Access the full database to benchmark your company against relevant public comparables.

What are recent M&A transactions in Inspirna's sector and industry vertical?

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What are recent capital raises and funding rounds in Inspirna's' sector and industry vertical?

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