Company profile: Krystal Biotech
1.1 - Company Overview
Company description
- Provider of gene therapies, including FDA-approved VYJUVEK for delivering missing or defective genes to the skin; with focus on Autosomal Recessive Congenital Ichthyosis, Netherton Syndrome, Cystic Fibrosis, and Alpha-1 Antitrypsin Deficiency; and oncology development using a modified HSV-1 vector to deliver IL-12 and IL-2 to the tumor microenvironment for immune-mediated tumor clearance.
Products and services
- VYJUVEK: FDA-approved gene therapy that delivers missing or defective genes to the skin for patients with rare debilitating disorders
- Oncology: Modified HSV-1-based gene delivery system transporting IL-12 and IL-2 into the tumor microenvironment for immune-mediated tumor clearance
- Autosomal Recessive Congenital Ichthyosis (ARCI): TGM1-linked genetic dermatologic condition characterized by severe skin barrier defects and increased infection risk
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Krystal Biotech
Tepnel Pharma Services
HQ: United Kingdom
Website
- Description: Provider of independent contract research services supporting the drug development pipeline at the Rx/Dx interface, delivering quality control laboratory analysis to help advance precision medicine and a value healthcare system that improves patient outcomes; part of a leading global healthcare and diagnostics company.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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- Total funding raised: $●●●m
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RoslinCT
HQ: United Kingdom
Website
- Description: Provider of cell therapy CDMO services, including cGMP clinical and commercial manufacturing; process and analytical development; iPSC cell line development and manufacture; and CRISPR-edited cell therapy product development. Offers expertise across cell types, genetic modification, cell expansion, and analytical testing (multi-color flow cytometry, ELISA, qPCR).
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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GenoKey
HQ: Denmark
Website
- Description: Provider of AI-driven combinatorial analytics of genomic and clinical data via the PrecisionLife Innovation Engine to discover novel drug targets, identify drug repositioning candidates, and design diagnostic, prognostic and theranostic clinical decision support tools. Offers precision biopharma and healthcare solutions, including combinatorial risk scores to predict and prevent chronic diseases such as dementia, diabetes and cardiovascular diseases.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
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Renova Therapeutics
HQ: United States
Website
- Description: Provider of gene therapies for chronic diseases, focusing on cardiovascular and metabolic indications. Offerings include RT-100, a single-dose therapy to improve heart function in congestive heart failure; RT-200, a single intravenous therapy to normalize blood glucose in Type 2 Diabetes Mellitus; and paracrine gene therapy enabling systemic delivery of therapeutic genes.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
View full Renova Therapeutics company profile →
Synlab
HQ: Germany
Website
- Description: Provider of laboratory diagnostics for human and veterinary medicine and environmental analysis services. Delivers wide-ranging laboratory testing, specialty and genetic testing (including preimplantation), supported by 2,000+ medical experts across 30+ countries and 2,000+ blood collection points. Also focuses on medical supplies trade, clinical trials, and consulting.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
View full Synlab company profile →
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2.M&A buyers
2.1 Potential strategic acquirers in the sector
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2.2 - Strategic buyer groups for Krystal Biotech
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3. Investors and private equity firms
3.1 - Buyout funds investing in similar companies to Krystal Biotech
2.2 - Growth funds investing in similar companies to Krystal Biotech
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4 - Top valuation comps for Krystal Biotech
4.2 - Public trading comparable groups for Krystal Biotech
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