Company profile: Apogee Therapeutics
1.1 - Company Overview
Company description
- Provider of antibody therapeutics for immunological and inflammatory disorders, including APG777 targeting IL-13 for atopic dermatitis, APG808 targeting IL-4Rα for chronic obstructive pulmonary disease, APG990 targeting OX40L for atopic dermatitis (preclinical), and APG222 dual-inhibiting OX40L and IL-13 for atopic dermatitis; designed for extended half-life and potentially less frequent dosing.
Products and services
- APG777: An antibody therapeutic targeting IL-13 for atopic dermatitis, engineered for extended half-life and potentially less frequent dosing
- APG808: An antibody therapeutic targeting IL-4Rα for chronic obstructive pulmonary disease, developed for extended half-life and potentially less frequent dosing
- APG222: A preclinical dual-inhibition antibody therapeutic targeting both OX40L and IL-13 for atopic dermatitis, unifying dual targets in one therapy
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Apogee Therapeutics
Hansa Biopharma
HQ: Sweden
Website
- Description: Provider of immunomodulatory treatments for rare immunological diseases, including Imlifidase, a first-generation IgG-cleaving enzyme for rapid inactivation of IgG antibodies via single intravenous treatment. Offers a proprietary enzyme technology platform targeting pathogenic antibodies across transplantation, autoimmunity, gene therapy and oncology, supported by strategic partnerships and sustainability initiatives.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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Fumapharm
HQ: Switzerland
Website
- Description: Provider of pharmaceuticals as a privately held company.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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Citryll
HQ: The Netherlands
Website
- Description: Provider of pharmaceutical drugs targeting Neutrophil Extracellular Traps (NETs) to treat autoimmune and inflammatory diseases such as SLE, RA, vasculitis, and IPF. Offers CIT-013, a therapeutic antibody; conducts NETosis inhibition research to reduce auto-antigen release and clear pro-inflammatory NETs; advances clinical development with first-in-human and planned Phase 2a trials in RA and hidradenitis suppurativa; and pursues collaboration opportunities.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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Sparrow Pharmaceuticals
HQ: United States
Website
- Description: Provider of clinical-stage biopharmaceutical therapies for disorders of corticosteroid excess, including SPI-62, an oral HSD-1 inhibitor designed to reduce intracellular cortisol in conditions like endogenous Cushingās syndrome and autonomous cortisol secretion, and SPI-47, combining SPI-62 with prednisolone for autoimmune diseases such as polymyalgia rheumatica.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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NorthSea Therapeutics
HQ: The Netherlands
Website
- Description: Provider of first-in-class, oral, structurally engineered lipid therapeutics leveraging Structurally Engineered Fatty Acid (SEFA) technology to target metabolic, inflammatory and fibrotic diseases. Pipeline includes Icosabutate (Phase 2b for NASH), SEFA-1024 (Phase 1 for severe hypertriglyceridemia), and SEFA-6179 (Phase 1 for intestinal failure-associated liver disease).
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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2.M&A buyers
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2.2 - Strategic buyer groups for Apogee Therapeutics
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3. Investors and private equity firms
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4 - Top valuation comps for Apogee Therapeutics
4.2 - Public trading comparable groups for Apogee Therapeutics
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