Company profile: Vaxart
1.1 - Company Overview
Company description
- Provider of oral vaccine pills and vaccine technology for infectious diseases, including COVID-19 (Phase II, room-temperature stable for easier global distribution), norovirus (Phase 1), influenza (Phase 1 completed for H1N1 and influenza B), RSV (targeting vulnerable populations), and an HPV therapeutic vaccine for types 16 and 18, built on the VAASTβ’ platform using Ad5 to deliver antigens and adjuvants to mucosal cells.
Products and services
- VAASTβ’ Platform: A proprietary system that uses adenovirus type 5 to deliver vaccine antigens and adjuvants directly to mucosal cells, enabling diverse oral vaccines
- COVID-19 Vaccine Pill: A room-temperature-stable oral pill that protects against COVID-19, currently in Phase II clinical trials, facilitating easier global distribution
- Norovirus Vaccine Pill: A clinical-stage oral pill targeting norovirus, with Phase 1 studies showing it is well tolerated and generates robust immune responses in recipients
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Vaxart
Replimune
HQ: United States
Website
- Description: Provider of next-generation oncolytic immunotherapies for cancer, developing proprietary products that enhance direct anti-tumor effects of selective virus replication and boost immune responses to tumor antigens. Products include RP1 (HSV-1 strain with immune-activating transgenes), RP2 (anti-CTLA-4 antibody targeting immunologically silent tumors to enhance tumor killing and immune response), and RP3 (CD40L and 4-1BBL ligands).
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: βββββ
- Total funding raised: $βββm
- Backers: ββββββββββ
- Acquisitions: ββ
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Maverick Therapeutics
HQ: United States
Website
- Description: Provider of T cell immunotherapies for solid tumor cancers, developing breakthrough treatments with improved safety and efficacy via COBRA, the most advanced bispecific T cell engaging platform in its class designed to safely target solid tumors.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: βββββ
- Total funding raised: $βββm
- Backers: ββββββββββ
- Acquisitions: ββ
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GT Biopharma
HQ: United States
Website
- Description: Provider of TriKE immunotherapy technology that bridges natural killer cells to cancer cells to boost anti-tumor responses. Pipeline includes GTB-3550 for CD33+ leukemias (AML, high-risk MDS), GTB-3650 using camelid nanobodies for CD33+ leukemias, and GTB-5550, GTB-4550, GTB-6550 for B7H3, PD-L1, and HER2 positive solid tumors.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: βββββ
- Total funding raised: $βββm
- Backers: ββββββββββ
- Acquisitions: ββ
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MinervaX
HQ: Denmark
Website
- Description: Provider of a biotechnology solution developing a novel vaccine against Group B Streptococcus (GBS) using a fusion protein shown to elicit protective immunity; offering the AlpN GBS Vaccine candidate designed for pregnant women and older adults to prevent GBS infections and likely protect against many clinically relevant GBS strains.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: βββββ
- Total funding raised: $βββm
- Backers: ββββββββββ
- Acquisitions: ββ
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Grid Therapeutics
HQ: United States
Website
- Description: Provider of AI-driven platforms and therapeutics for cancer, including GT103, a human-derived antibody targeting a tumor-specific epitope for lung and other cancers. Offerings include high-throughput antibody discovery without prior protein knowledge, an AI-driven data warehouse, computational biology tools, a tumor vaccine design program, and a Phase 1b NSCLC study of GT103.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: βββββ
- Total funding raised: $βββm
- Backers: ββββββββββ
- Acquisitions: ββ
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2.M&A buyers
2.1 Potential strategic acquirers in the sector
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2.2 - Strategic buyer groups for Vaxart
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Buyer group 1: ββββββββ ββββββββ
ββ companies
Description: ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ
Key Products: ββββββββ, ββββββββ, ββββββββ, ββββββββ
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Buyer group 2: ββββββββ ββββββββ
ββ companies
Description: ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ
Key Products: ββββββββ, ββββββββ, ββββββββ, ββββββββ
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Buyer group 3: ββββββββ ββββββββ
ββ companies
Description: ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ ββββββββ
Key Products: ββββββββ, ββββββββ, ββββββββ, ββββββββ
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3. Investors and private equity firms
3.1 - Buyout funds investing in similar companies to Vaxart
2.2 - Growth funds investing in similar companies to Vaxart
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4 - Top valuation comps for Vaxart
4.2 - Public trading comparable groups for Vaxart
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