Company profile: Kairos Pharma
1.1 - Company Overview
Company description
- Provider of clinical-stage cancer immunotherapies addressing drug resistance: ENV-105 (Endoglin-targeting antibody; Phase I/II for prostate and lung), KROS-201 (activated T cell therapy for glioblastoma), KROS-101 (GITR agonist), KROS-102 (GITR antagonist), KROS-301 (RelA/NF-ÎșB inhibitor), and KROS-401 (IL4/IL13 cyclic peptide for triple-negative breast cancer, with radiation).
Products and services
- ENV-105: Clinical-stage antibody targeting Endoglin to reverse resistance in prostate and lung cancer treatments, with active Phase I and Phase II clinical trials
- KROS-301: Small-molecule inhibitor blocking intranuclear RelA localization, targeting the NF-KB pathway to kill tumor cells in RelA/p65 biomarker-positive solid tumors
- KROS-101: Small-molecule GITR agonist engineered to deplete regulatory T cells and activate effector T cells, enhancing the antitumor immune response
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Kairos Pharma
FogPharma
HQ: United States
Website
- Description: Provider of precision medicines based on Helicons, a new class combining antibody-like targeting with broad tissue distribution and intracellular target engagement of small molecules; pipeline includes FOG-001, a first-in-class TCF-blocking ÎČ-catenin inhibitor (Phase 1/2), ÎČ-catenin and ERG degraders, an ERG/DNA binding inhibitor (discovery), and Helicon-enabled alpha radioligand therapies (hit identification).
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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- Total funding raised: $âââm
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Theriva Biologics
HQ: United States
Website
- Description: Provider of biologics for the prevention and treatment of serious infectious diseases.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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- Total funding raised: $âââm
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MAIA Biotechnology
HQ: United States
Website
- Description: Provider of immuno-oncology drug R&D, developing first-in-class therapies with novel mechanisms, including THIO, an investigational telomere-targeting candidate that induces immune responses in cancer cells (Phase 2 in non-small cell lung cancer), and second-generation telomere-targeting agents in early discovery.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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- Total funding raised: $âââm
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IsoPlexis
HQ: United States
Website
- Description: Provider of single-cell detection technology that identifies a wide range of patient immune responses at the single-cell level. Its platform assesses the safety and efficacy of therapeutics and monitors disease progression to support improved therapeutic development and inform physician decisions.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: âââââ
- Total funding raised: $âââm
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Ajax Therapeutics
HQ: United States
Website
- Description: Provider of therapies targeting cytokine signaling in hematologic malignancies, including AJ1-10502, a next-generation Type II JAK2 inhibitor for myeloproliferative neoplasms with improved efficacy and selectivity over Type I JAK2 inhibitors, and developer of a pipeline of selectively targeted small molecules via a partnership with Schrödinger using advanced computational chemistry and structure-based technologies.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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- Total funding raised: $âââm
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2.M&A buyers
2.1 Potential strategic acquirers in the sector
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2.2 - Strategic buyer groups for Kairos Pharma
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3. Investors and private equity firms
3.1 - Buyout funds investing in similar companies to Kairos Pharma
2.2 - Growth funds investing in similar companies to Kairos Pharma
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4 - Top valuation comps for Kairos Pharma
4.2 - Public trading comparable groups for Kairos Pharma
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