Company profile: Evommune
1.1 - Company Overview
Company description
- Provider of therapeutics to halt progressive disease and address symptoms, focused on chronic inflammatory diseases. Develops EVO756, an oral, highly selective MRGPRX2 inhibitor for chronic spontaneous urticaria despite H1 antihistamines; a PKCĪø inhibitor to regulate immune response; collaborative drug discovery with partners like Accutar; and clinical trial programs, including Phase 1 for EVO756.
Products and services
- EVO756: Orally administered, highly selective MRGPRX2 inhibitor being developed for chronic spontaneous urticaria patients remaining symptomatic despite H1 antihistamines, with Phase 1 studies assessing safety, tolerability, and efficacy
- Clinical Trials: Phase 1āoriented programs constructed to evaluate safety, tolerability, and efficacy of investigational therapies for chronic inflammatory diseases, including Phase 1 trials for EVO756
- PKCĪø Inhibitor: Evommune engineers a small-molecule inhibitor targeting Protein Kinase C Theta (PKCĻ“) to regulate immune cell response, with potential applications across immune-mediated chronic inflammatory diseases
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Evommune
PureTech Health
HQ: United States
Website
- Description: Provider of biopharma therapies and platforms, including KarXT for schizophrenia (xanomeline + trospium), LYT-100 (deuterated pirfenidone) for idiopathic pulmonary fibrosis, LYT-200 (anti-galectin-9) for hematological malignancies and solid tumors, SPT-300 (oral allopregnanolone) for neurological and neuropsychiatric conditions, plus Vedanta's microbiome-based oral therapies and Entrega's hydrogel-enabled oral biologics.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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Corbus Pharmaceuticals
HQ: United States
Website
- Description: Provider of clinical-stage therapeutics targeting inflammatory and fibrotic diseases, with programs in oncology and obesity. Pipeline includes CRB-701, a next-generation Nectin-4-targeting ADC in trials for advanced solid tumors; CRB-601, an anti-integrin monoclonal antibody blocking TGFβ activation on cancer cells; and CRB-913, a peripherally restricted CB1 inverse agonist for obesity with IND planned.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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IMMCO Diagnostics
HQ: United States
Website
- Description: Provider of innovative medical devices, diagnostic laboratory testing expertise, and pioneering research for a comprehensive solution to autoimmune disease diagnostics.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
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Sitryx
HQ: United Kingdom
Website
- Description: Provider of cell metabolismātargeted, first-in-class, disease-modifying therapeutics in immuno-oncology and immuno-inflammation. Pipeline includes SYX-5219 for atopic dermatitis; SIT-052, an inhaled GLS1 inhibitor for pulmonary fibrosis and COPD that selectively breaks down senescent cells; SIT-033, a SIK2 inhibitor for ulcerative colitis; and SYX-1042 and SIT-047 for autoimmune indications (with Eli Lilly).
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
- Backers: āāāāāāāāāā
- Acquisitions: āā
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Fresh Tracks Therapeutics
HQ: United States
Website
- Description: Provider of pharmaceutical therapeutics for autoimmune, inflammatory, and debilitating diseases.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: āāāāā
- Total funding raised: $āāām
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2.M&A buyers
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2.2 - Strategic buyer groups for Evommune
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3. Investors and private equity firms
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4 - Top valuation comps for Evommune
4.2 - Public trading comparable groups for Evommune
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