Company profile: Northwest Biotherapeutics
1.1 - Company Overview
Company description
- Provider of cancer immunotherapy products, focused on developing and commercializing personalized vaccine candidates: DCVax-L for newly diagnosed glioblastoma multiforme (GBM) in a Phase III trial; DCVax-Direct for direct injection into inoperable solid tumors in a Phase I/II trial; and DCVax-Prostate targeting late-stage, hormone-independent prostate cancer using a proprietary PSMA antigen.
Products and services
- DCVax-Direct: Engineers a clinical-stage, direct-injection immunotherapy for inoperable solid tumor cancers, currently in a Phase I/II trial
- DCVax-L: Produces a personalized vaccine for newly diagnosed GBM, undergoing evaluation in a Phase III trial
- DCVax-Prostate: Constructs a proprietary-antigen, PSMA-based vaccine targeting late-stage, hormone-independent prostate cancer, utilizing prostate-specific membrane antigen as the vaccine target
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Northwest Biotherapeutics
Atrin Pharmaceuticals
HQ: United States
Website
- Description: Provider of biopharmaceutical discovery and development for innovative cancer treatments. The privately held company, based in Doylestown, PA, is engaged in the discovery and development of treatments for cancer, with its most advanced program focused on a new class of highly specific compounds.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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Flare Therapeutics
HQ: United States
Website
- Description: Provider of precision therapies by targeting transcription factors, including FX-909, a first-in-class small molecule PPARG inhibitor in Phase 1 for advanced solid malignancies such as advanced urothelial carcinoma. Offers a discovery engine and a pipeline of TF-targeted drug programs, with switch site identification, ligandability, and pharmacology capabilities, initially focused on precision oncology and expanding to metabolic, neurology, immunology/inflammation, and rare genetic disorders.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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- Total funding raised: $●●●m
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ScreenPoint Medical
HQ: The Netherlands
Website
- Description: Provider of deep learning and image analysis technology for automated reading of mammograms and digital breast tomosynthesis. Offers Transpara software that assists radiologists by categorizing and prioritizing exams, differentiating those with a high probability of suspicious findings, and providing workflow enhancements, combining machine learning advances with very large, well-curated digital image databases.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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Oncimmune
HQ: United Kingdom
Website
- Description: Provider of proprietary autoantibody assay technologies for early cancer detection, offering ImmunoINSIGHTS analytical platform to discover and profile autoantibody biomarkers for disease characterization, patient stratification, and response prediction; biomarker discovery services; customizable targeted panels and arrays for immuno-oncology and autoimmune diseases; and bioinformatics and data science with multiomics integration.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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Compass Therapeutics
HQ: United States
Website
- Description: Provider of immune system–targeting therapeutics and antibody engineering platforms. Pipeline: CTX-009, a DLL4/VEGF-A bispecific showing benefit in colorectal and gastric cancers; CTX-471, a CD137 agonist for melanoma with U.S. studies planned H2 2024; and CTX-8371, a PD-1/PD-L1 bispecific in preclinical development for solid tumors. Platforms: StitchMabs for bispecifics, common light chain discovery, and human display for antibody tuning.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
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2.M&A buyers
2.1 Potential strategic acquirers in the sector
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2.2 - Strategic buyer groups for Northwest Biotherapeutics
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3. Investors and private equity firms
3.1 - Buyout funds investing in similar companies to Northwest Biotherapeutics
2.2 - Growth funds investing in similar companies to Northwest Biotherapeutics
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4 - Top valuation comps for Northwest Biotherapeutics
4.2 - Public trading comparable groups for Northwest Biotherapeutics
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