Company profile: Trethera
1.1 - Company Overview
Company description
- Provider of small-molecule therapeutics that control DNA replication and integrity, including TRE-515, an orally bioavailable inhibitor of deoxycytidine kinase (dCK) targeting the nucleotide salvage pathway to treat solid tumors and autoimmune diseases.
Products and services
- TRE-515: An orally-bioavailable inhibitor of deoxycytidine kinase (dCK) that targets the nucleotide salvage pathway to treat solid tumors and autoimmune diseases
- Small-Molecule Development: Develops small molecules that control DNA replication and integrity, advancing compounds that modulate DNA replication and integrity
- Small-Molecule Discovery: Discovers small molecules that control DNA replication and integrity, identifying compounds that modulate DNA replication and integrity
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Trethera
U3 Pharma
HQ: Germany
Website
- Description: Provider of targeted cancer drug development and novel targeted therapeutics, based in Martinsried near Munich, Germany. Established in 2001, U3 Pharma develops a pipeline of targeted therapies grounded in discoveries by founder Professor Axel Ullrich. Since May 2008, the company has belonged to DAIICHI Sankyo Co., Ltd.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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- Total funding raised: $●●●m
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Marengo Therapeutics
HQ: United States
Website
- Description: Provider of T cell–modulating antibody platforms and therapeutics, including the STAR bi-functional molecule platform pairing anti-Vβ antibodies with costimulatory signals for antigen-rich 'hot' tumors; the TriSTAR T cell engager for antigen-low 'cold' tumors; TCR-targeting antibodies; an antibody technology platform using genomics and TCR sequencing; and STAR0602, in Phase I/II (START-001) for advanced antigen-rich solid tumors.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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Cellectis
HQ: France
Website
- Description: Provider of adoptive cancer immunotherapies, developing allogeneic CAR T candidates including UCART22 for r/r B-ALL, UCART123 targeting CD123 for AML, and UCART20x22 targeting CD20/CD22 for B-cell malignancies, plus TALEN gene editing and PulseAgile electroporation technologies.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
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Rain Oncology
HQ: United States
Website
- Description: Provider of precision oncology therapies targeting oncogenic drivers, developing milademetan, an oral small molecule inhibitor of the p53-MDM2 complex for various cancers. Clinical programs include MANTRA (Phase 3 in dedifferentiated liposarcoma), MANTRA-2 (Phase 2 in TP53 wildtype/MDM2-amplified solid tumors), and MANTRA-4 (Phase 1/2 with atezolizumab in CDKN2A loss, TP53 wildtype tumors).
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
View full Rain Oncology company profile →
Oncogeni
HQ: United Kingdom
Website
- Description: Provider of novel cell- and RNA-based cancer medicines, specializing in small interfering RNA and mesodermal killer cells.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
View full Oncogeni company profile →
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2.M&A buyers
2.1 Potential strategic acquirers in the sector
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2.2 - Strategic buyer groups for Trethera
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Buyer group 3: ████████ ████████
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3. Investors and private equity firms
3.1 - Buyout funds investing in similar companies to Trethera
2.2 - Growth funds investing in similar companies to Trethera
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4 - Top valuation comps for Trethera
4.2 - Public trading comparable groups for Trethera
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