Company profile: Arvinas
1.1 - Company Overview
Company description
- Provider of PROTAC protein degrader therapies that harness the body's natural protein disposal system to degrade disease-causing proteins for life-threatening diseases, from discovery to commercialization. Pipeline includes vepdegestrant (ER+ breast cancer), ARV-766 (licensed to Novartis; prostate cancer), ARV-393 (BCL6), ARV-102 (LRRK2), and alpha-synuclein degraders.
Products and services
- Vepdegestrant: An oral PROTAC protein degrader targeting the estrogen receptor to treat ER+ breast cancer disease
- ARV-766: A PROTAC androgen receptor protein degrader for prostate cancer, licensed to Novartis for development and commercialization
- ARV-393: An investigational PROTAC designed to degrade B-cell lymphoma 6 protein, implicated in B cell lymphomas
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Arvinas
ProfoundBio
HQ: United States
Website
- Description: Provider of antibody-based cancer therapeutics, including antibody-drug conjugates. Clinical-stage pipeline includes Rina-S, a folate receptor alpha-targeting ADC for ovarian and other solid tumors (Phase 2); PRO1160, a CD70-targeting ADC for solid tumors and hematological malignancies (Phase 1/2); PRO1107, a PTK7-targeted ADC with a hydrophilic MMAE-based linker-drug (Phase 1/2); and PRO1286, a bispecific EGFR/cMET ADC (trials anticipated in 2024).
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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- Total funding raised: $●●●m
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RadiaDyne
HQ: United States
Website
- Description: Provider of medical diagnostics and devices; privately held.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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Cirrus Bio
HQ: United States
Website
- Description: Provider of solutions for common health issues that impact well-being.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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YM BioSciences
HQ: Canada
Website
- Description: Provider of life sciences product development services focused on identifying and advancing a diverse portfolio of cancer-related products at various stages of development, leveraging regulatory and clinical trial expertise and a diversified business model to reduce risk while advancing clinical products.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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Orionis Biosciences
HQ: United States
Website
- Description: Provider of biotechnology platforms for healthcare innovation, including the A-Kine platform for engineering cytokines with targeted cell selectivity and controlled activity for cancer immunotherapy, and the Allo-Glue platform for discovering and designing small molecule molecular glues to modulate or degrade disease targets.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
View full Orionis Biosciences company profile →
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2.M&A buyers
2.1 Potential strategic acquirers in the sector
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2.2 - Strategic buyer groups for Arvinas
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3. Investors and private equity firms
3.1 - Buyout funds investing in similar companies to Arvinas
2.2 - Growth funds investing in similar companies to Arvinas
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4 - Top valuation comps for Arvinas
4.2 - Public trading comparable groups for Arvinas
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