Company profile: Pharvaris
1.1 - Company Overview
Company description
- Provider of oral bradykinin B2-receptor antagonist therapies in clinical development for hereditary angioedema (HAE), including deucrictibant; PHVS416 immediate-release capsules for acute HAE attacks; PHVS719 extended-release tablets for HAE prophylaxis; and the RAPIDe-1, RAPIDe-2, and CHAPTER-1 clinical trials evaluating these candidates.
Products and services
- Deucrictibant: A clinical-stage oral bradykinin B2-receptor antagonist in development to treat hereditary angioedema, employing novel small molecules as alternatives to injected therapies across HAE sub-types
- PHVS719: An extended-release tablet developed to maintain therapeutic exposure for over 24 hours, intended for prophylactic treatment of hereditary angioedema via sustained oral B2-receptor antagonism
- PHVS416: An immediate-release capsule engineered for rapid therapeutic exposure to treat acute hereditary angioedema attacks, designed for fast on-demand use assessed in clinical studies
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Pharvaris
Cydan
HQ: United States
Website
- Description: Provider of orphan drug accelerator services focused on identifying and de-risking compounds with therapeutic and commercial potential.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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Astria Therapeutics
HQ: United States
Website
- Description: Provider of drug discovery and development for inflammatory conditions, with a pipeline including STAR-0215, a monoclonal antibody inhibitor of plasma kallikrein for long-acting prevention of hereditary angioedema (potentially dosed every 3 to 6 months), STAR-0310, a monoclonal antibody OX40 antagonist for atopic dermatitis, and the ALPHA-STAR Phase 1b/2 trial evaluating STAR-0215 in HAE types I and II.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
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Aeovian Pharmaceuticals
HQ: United States
Website
- Description: Provider of therapeutics for rare and age-related diseases, focused on discovering, developing, and commercializing treatments.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
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Mitobridge
HQ: United States
Website
- Description: Provider of small molecule therapeutics that improve mitochondrial function to address diseases with high unmet need. Pipeline includes investigational candidates: ASP0367 for primary mitochondrial myopathies and Duchenne muscular dystrophy, ASP1128 for acute kidney injury, and an NAD+ modulation program targeting aging-related conditions.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
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Chiasma
HQ: United States
Website
- Description: Provider of biopharmaceutical solutions developing oral drugs for orphan diseases using proprietary Transient Permeability Enhancer technology to convert approved injectables to oral formulations, potentially enabling new indications and enhanced absorption by promoting delivery to the GI wall and liver.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
View full Chiasma company profile →
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2.M&A buyers
2.1 Potential strategic acquirers in the sector
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2.2 - Strategic buyer groups for Pharvaris
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3. Investors and private equity firms
3.1 - Buyout funds investing in similar companies to Pharvaris
2.2 - Growth funds investing in similar companies to Pharvaris
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4 - Top valuation comps for Pharvaris
4.2 - Public trading comparable groups for Pharvaris
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