Company profile: Definigen
1.1 - Company Overview
Company description
- Provider of in-vitro liver and metabolic disease models using iPSC technology to generate pre-clinical human data, offering Opti-HEPs for drug efficacy and predictive toxicology screening, phenotypic screening with bioassays, and custom disease model development via CRISPR. Includes models for Alpha-1 Antitrypsin Deficiency, Wilson's Disease (ATP7B), and Glycogen Storage Disease Type 1 Alpha.
Products and services
- Phenotypic Screening Service: Assay-integrated service combining iPSC-derived hepatocyte models with bioassays to screen therapeutic candidates and generate pre-clinical human data in liver and metabolic disease contexts
- Custom Model Development: Custom-engineered service architecting tailored disease models with CRISPR gene editing and iPSC technology to support drug discovery in liver and metabolic disease research
- Opti-HEPs: Research-grade iPSC-derived hepatocyte-like cells engineered via the OptiDIFF platform for drug efficacy testing and predictive toxicology screening in in-vitro liver and metabolic disease models
Key contacts
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Financial details
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1.2 - Competitors and similar companies to Definigen
Purolite
HQ: United Kingdom
Website
- Description: Provider of pharmaceutical resin products used as APIs or excipients; marketed APIs cholestyramine and sodium polystyrene sulfonate; excipients for taste-masking, carriers, and disintegrants; PuroMill pharmaceutical-grade milling media for nanoparticles <100 nm to enhance solubility; and polymeric and chromatography resins for biofluid treatment, separation, purification, and medical device diagnostic and treatment applications.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
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Nanalysis
HQ: Canada
Website
- Description: Provider of portable benchtop nuclear magnetic resonance (NMR) spectrometers and supporting software for biotech, pharmaceutical, research, and education applications. Offerings include 100 MHz and 60 MHz NMR spectrometers, NMReady-CONNECT for remote control/monitoring, pulse sequence design, time-based kinetics experiments, and IQ/OQ modules for performance validation and regulatory compliance.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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Seraxis
HQ: United States
Website
- Description: Provider of cell replacement therapy and lab-grown pancreatic islets for insulin-dependent diabetes. Offerings include SR-01, which combines lab-grown human islets with a technology to implant these islets without immune suppression; SR1423, a stem cell line maturing into insulin-secreting islets; and lab-grown islets that mimic native pancreatic function and respond to glucose.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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PanThera CryoSolutions
HQ: Canada
Website
- Description: Provider of cryopreservation solutions for cells, tissues, and organs, featuring IRIs that control ice crystal size and growth to improve cell recovery/quality and reduce warming damage; IRIs mitigate toxicity of conventional cryoprotective agents to enable higher sub-zero storage temperatures, with GMP-compliant manufacturing and less costly storage/transport, restricting liquid nitrogen use in some cell treatment applications.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
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Cellix
HQ: Ireland
Website
- Description: Provider of microfluidic pumping solutions, consumable biochips, software, and automated solutions for cell biology, microfluidics and nanofluidics, physics, chemistry, and cell and particle studies. Offerings include pulse-free syringe, pressure and recirculating pumps with PC control, VenaFlux for shear flow assays, the Inish Analyser for label-free cell counting, viability and transfection efficiencies, and disposable biochips for flow and droplet studies.
- Rationale: This competitor operates in a highly similar market segment with overlapping features.
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
- Backers: ●●●●●●●●●●
- Acquisitions: ●●
View full Cellix company profile →
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2.M&A buyers
2.1 Potential strategic acquirers in the sector
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2.2 - Strategic buyer groups for Definigen
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3. Investors and private equity firms
3.1 - Buyout funds investing in similar companies to Definigen
2.2 - Growth funds investing in similar companies to Definigen
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4 - Top valuation comps for Definigen
4.2 - Public trading comparable groups for Definigen
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