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Clinical Digital Therapeutics Platforms sector

Strategic acquirers, private equity (buyout funds and growth funds) firms, and valuation benchmarks for Clinical Digital Therapeutics Platforms

1.1 - About Clinical Digital Therapeutics Platforms sector

Companies in the Clinical Digital Therapeutics Platforms category build software-based interventions that deliver evidence-based treatment for chronic, mental, and specialty conditions. They provide prescription-grade programs, remote monitoring, and clinician oversight to augment or replace traditional therapies. These vendors enable regulated, measurable outcomes via mobile apps, connected devices, and data platforms, supporting care pathways, adherence, and reimbursement workflows for health systems, payers, and life sciences partners.

Offerings typically include FDA-cleared or CE-marked prescription digital therapeutics with disease-specific protocols, cognitive behavioral therapy modules, and guided behavior change. Vendors pair remote patient monitoring via sensors and wearables with clinician dashboards for titration, alerts, and care-plan management, and integrate through FHIR/EHR APIs. Many provide AI-driven personalization, outcomes analytics and real‑world evidence generation, HIPAA/GDPR-compliant data security, and reimbursement support such as coding, prior authorization, and patient enrollment.

These companies primarily serve health systems and integrated delivery networks, health plans and payers, and pharmaceutical manufacturers seeking companion or virtual therapeutics. Customers use these platforms to improve clinical outcomes and adherence, scale access to evidence-based care, reduce total cost of care through fewer hospitalizations, and generate real‑world evidence to inform reimbursement and regulatory strategy, making them attractive strategic buyers in clinical digital therapeutics.

2. Buyers in the Clinical Digital Therapeutics Platforms sector

2.1 Top strategic acquirers of Clinical Digital Therapeutics Platforms companies

Hinge Health Logo

Hinge Health

HQ: United States Website
  • Description: Provider of a digital clinic that treats and prevents joint and muscle pain by connecting members digitally and in-person with AI-powered clinical teams through a mobile app, guiding personalized musculoskeletal care that has reduced pain by 68%, prevented 42% of opioid prescriptions and avoided over half of joint-replacement surgeries.
  • Key Products:
  • Digital Clinic for Joint & Muscle Pain: Mobile app delivers AI-guided exercise therapy, virtual coaching and in-person support to reduce pain and prevent surgeries for MSK conditions
  • HingeSelect High-Performance Network: Integrates digital platform with vetted orthopedic specialists, physical therapists and imaging centers, offering 48-hour access, in-app scheduling and bundled pricing below PPO rates
  • Employer & Health Plan MSK Solution: Provides unified end-to-end musculoskeletal care enabling organizations to lower MSK spend while ensuring quality care for every member
  • Personalized Whole-Person Care Approach: Connects MSK treatment with mental health and weight factors, offering tailored programs that address pain drivers and improve overall outcomes.
  • Company type: Private company
  • Employees: ●●●●●
  • Total funding raised: $●●●m
  • Backers: ●●●●●●●●●●
  • Acquisitions: ●●
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2.2 - Strategic buyer groups for Clinical Digital Therapeutics Platforms sector

M&A buyer group 1: Chronic Disease Management

81 companies View group →
Description: Companies in the Enterprise Chronic Care Management Platforms category build configurable, evidence-based digital health software for ongoing management of cardiometabolic, oncology, and behavioral conditions. Strategic buyers in this space connect devices for real-time remote monitoring, deliver digital interventions and coaching, and surface clinical insights via analytics, helping providers and payers personalize care, intervene earlier, scale programs across populations, and support regulatory-grade workflows, integration, and reimbursement.
Huma

Huma

HQ: United Kingdom
  • Type: N/A
  • Employees: ●●●●●
  • Description: Provider of AI-driven digital health solutions that include a cloud platform for rapidly building regulated health apps, remote patient monitoring, virtual wards and clinical trial tools, plus AI modules that automate documentation, triage and care workflows to optimise patient outcomes.
  • Key Products:
  • Huma Cloud Platform: Highly configurable, flexible, disease-agnostic cloud infrastructure offering code-free configuration, multi-device connectivity and hosting of AI/ML models with multiple regulatory clearances for rapid digital health solution deployment
  • Remote Patient Monitoring Programmes: Programmes capture real-world health data, enable continuous remote monitoring and self-management, empowering proactive, preventative care while reducing hospital burden
  • Companion Apps: Mobile companion applications integrate with the platform to support online or face-to-face consultations, deliver personalised insights and guide patients through their health journeys
  • Risk Assessment Tools & AI Algorithms: AI-powered, including generative AI, algorithms analyse patient histories to generate personalised risk assessments, predictive insights and optimise treatment outcomes for clinicians and researchers.
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Buyer group 2: ████████ ████████

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Key Products: ████████, ████████, ████████, ████████
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Buyer group 3: ████████ ████████

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Description: ████████ ████████ ████████ ████████ ████████ ████████ ████████ ████████ ████████ ████████
Key Products: ████████, ████████, ████████, ████████
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3. Investors and private equity firms in Clinical Digital Therapeutics Platforms sector

3.1 - Buyout funds in the Clinical Digital Therapeutics Platforms sector

Buyout Funds investing in Clinical Digital Therapeutics Platforms companies

51+ funds
Description: Buyout funds focused on Clinical Digital Therapeutics Platforms companies globally.

Francisco Partners

Website HQ: United States
  • Type: Buyout
  • Fund Size: $●●●m
  • Investment Range: $●●-●●●m
  • Focus: Technology companies in Clinical Digital Therapeutics Platforms
  • Relevant M&A transactions / similar portfolio companies:
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2.2 - Strategic buyer groups for Clinical Digital Therapeutics Platforms sector

Growth Equity Funds in Clinical Digital Therapeutics Platforms companies

41+ funds
Description: Growth equity funds focused on Clinical Digital Therapeutics Platforms companies globally.

Summit Partners

Website HQ: United States
  • Type: Growth
  • Fund Size: $●●●m
  • Investment Range: $●●-●●●m
  • Focus: High-growth companies in Clinical Digital Therapeutics Platforms
  • Relevant investments / similar portfolio companies:
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4 - Top valuation comps for Clinical Digital Therapeutics Platforms companies

4.2 - Public trading comparable groups for Clinical Digital Therapeutics Platforms sector

Description: Companies in this trading comparable group are public software providers delivering population health management and analytics platforms to healthcare providers and payers. They monetize via SaaS subscriptions, per-member-per-month fees, and technology-enabled services that support value-based care, care coordination, and clinical decision support. They are comparable given similar data-driven offerings, customer bases, and recurring revenue models focused on outcomes and cost reduction.
Privia Health logo

Privia Health

  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of technology-driven healthcare solutions, optimizing physician practices, enhancing patient experiences, and rewarding doctors for high-value care through collaboration with medical groups, health plans, and health systems.
  • Key Products:
  • Practice Management: Tools and services to optimize physician practices
  • Patient Portal: Platform for patient engagement and communication
  • Value-Based Care: Strategies to improve care quality and reduce costs
  • Virtual Care: Telehealth services for remote patient consultations
  • Fitness and Nutrition Plans: Personalized health assessments and plans for patients
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Revenue growth
Median
15.7%
2025E
16.0%
2026E
EBITDA margin
Median
28.2%
2025E
28.6%
2026E
Cash EBITDA margin
Median
27.6%
2025E
28.0%
2026E
EV/Revenue
Median
8.4x
2025E
6.8x
2026E
EV/EBITDA
Median
28.9x
2025E
24.4x
2026E
EV/Cash EBITDA
Median
29.0x
2025E
25.5x
2026E
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4.3 - M&A Transactions in the Clinical Digital Therapeutics Platforms sector

Selected M&A transactions

Date Target Description Buyer(s) Relevance EV EV/Revenue EV/EBITDA
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Frequently Asked Questions

Buyers & Acquirers in Clinical Digital Therapeutics Platforms sector

Who are the top strategic acquirers of Clinical Digital Therapeutics Platforms companies?

Top strategic buyers in this sector include Hinge Health, a provider of a digital clinic that treats and prevents joint and muscle pain by connecting members digitally and in-person with ai-powered clinical teams through a mobile app, guiding personalized musculoskeletal care that has reduced pain by 68%, prevented 42% of opioid prescriptions and avoided over half of joint-replacement surgeries. .

Which buyer groups are most relevant for Clinical Digital Therapeutics Platforms companies?

Relevant strategic buyer groups similar to the Clinical Digital Therapeutics Platforms sector include Chronic Disease Management because they share similar customer segments and product capabilities.

Financial Investors in Clinical Digital Therapeutics Platforms sector

Which are the top PE firms investing in Clinical Digital Therapeutics Platforms companies?

Potential investors in the broader Clinical Digital Therapeutics Platforms space include Summit Partners and Francisco Partners.

Who are the top buyout funds acquiring Clinical Digital Therapeutics Platforms companies?

Active PE funds and buyout funds acquiring companies in the Clinical Digital Therapeutics Platforms space include Francisco Partners.

Who are the top growth equity funds investing in Clinical Digital Therapeutics Platforms companies?

Growth funds investing in the broader Clinical Digital Therapeutics Platforms sector include Summit Partners.

Valuation of Companies in Clinical Digital Therapeutics Platforms sector

Which are the key public companies that are relevant trading comps for Clinical Digital Therapeutics Platforms companies?

Key trading comparable groups include Privia Health, a provider of technology-driven healthcare solutions, optimizing physician practices, enhancing patient experiences, and rewarding doctors for high-value care through collaboration with medical groups, health plans, and health systems..

Which are the key trading comparable groups for Clinical Digital Therapeutics Platforms companies?

Similar trading comparable companies include Population Health Management Software Companies. Our platform tracks detailed trading comparable groups in the Clinical Digital Therapeutics Platforms sector with complete valuation multiples, growth metrics, and profitability data. Access the full database to benchmark your company against relevant public comparables.

What are recent M&A transactions in the Clinical Digital Therapeutics Platforms sector?

Our platform tracks M&A transactions in the Clinical Digital Therapeutics Platforms sector with complete deal terms, valuation multiples, and strategic rationale. Access the full database to benchmark pricing and identify active acquirers.

What are recent capital raises and funding rounds in Clinical Digital Therapeutics Platforms?

Access recent funding rounds in the Clinical Digital Therapeutics Platforms sector including growth equity, venture capital, and buyout investments. Our database includes round size, lead investors, valuations, and use of proceeds.

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