Life Sciences Immunotherapeutic Vaccine Platforms sector
Strategic acquirers, private equity (buyout funds and growth funds) firms, and valuation benchmarks for Life Sciences Immunotherapeutic Vaccine Platforms
1.1 - About Life Sciences Immunotherapeutic Vaccine Platforms sector
Companies in the Life Sciences Immunotherapeutic Vaccine Platforms category design, engineer, and manufacture therapeutic vaccines that activate patient immune responses, primarily in oncology and chronic infectious disease settings. They combine antigen discovery, vaccine formulation, and scalable GMP production to deliver personalized and off-the-shelf candidates. Strategic buyers in this space seek differentiated pipelines, proprietary delivery modalities, and data-driven development engines that improve clinical efficacy and development speed.
Typical offerings span computational neoantigen discovery engines and epitope prioritization workflows; peptide and mRNA vaccine design studios with LNP or viral vector delivery; dendritic cell and tumor lysate vaccine manufacturing suites; adjuvant libraries and TLR agonists for immune activation; immune monitoring assays and biomarker-guided patient selection; and end-to-end GMP manufacturing, QC release, and regulatory CMC support. Some vendors add oncolytic virus backbones and combination therapy optimization tools.
They serve oncology-focused biopharma sponsors, clinical-stage biotech developers, and academic medical centers running translational trials. Outcomes include accelerated candidate selection and IND timelines, improved response rates through personalized neoantigen targeting, reduced manufacturing risk with validated GMP processes, and stronger regulatory packages via standardized CMC and immunogenicity analytics. These capabilities help expand pipelines and de-risk late-stage development and combination strategies.
2. Buyers in the Life Sciences Immunotherapeutic Vaccine Platforms sector
2.1 Top strategic acquirers of Life Sciences Immunotherapeutic Vaccine Platforms companies
Brii Biosciences
- Description: Provider of biotechnology research and drug-development solutions focused on infectious and central nervous system diseases, offering a pipeline of differentiated investigational therapies built from patient insights to address high unmet medical needs, including candidates aimed at functional cures for hepatitis B and other public-health challenges.
- Key Products:
- BRII-179: recombinant protein-based immunotherapy expressing multiple HBV surface antigens to stimulate broad B-cell and T-cell immunity for curative HBV treatment
- Elebsiran: subcutaneous HBV-targeting siRNA that degrades viral RNA transcripts, lowers surface antigen levels and exhibits direct antiviral activity against HBV and HDV
- Tobevibart: subcutaneous neutralizing monoclonal antibody that blocks HBV/HDV entry into hepatocytes and reduces circulating virions, aiming to control chronic infections
- BRII-732: orally administered NCE prodrug converting to islatravir, enabling once-weekly long-acting combination therapy for HIV treatment and prevention
- Company type: Publicly traded
- Employees: ●●●●●
- Enterprise value: $●●●●m
- Cash & ST investments: $●●●●m
- EV/Revenue (NTM): ●●.●x
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2.2 - Strategic buyer groups for Life Sciences Immunotherapeutic Vaccine Platforms sector
M&A buyer group 1: Cancer Immunotherapy
Precigen
- Type: N/A
- Employees: ●●●●●
- Description: Provider of biotechnology solutions focused on human gene therapy and gene editing, leveraging proprietary DNA-engineering technologies to control cellular functions and develop treatments such as CAR-T therapies for acute myeloid leukemia.
- Key Products:
- PRGN-3006 CAR-T Therapy: Investigational CAR-T treatment granted orphan drug status targeting acute myeloid leukemia by genetically engineering patient T-cells to attack cancer cells and potentially improve clinical outcomes
- Proprietary DNA Engineering Platform: Suite of complementary technologies that enables precise DNA-based control over cellular functions, supporting creation of diverse gene and cell therapies
- Human Gene Editing Programs: Focused research initiatives applying advanced gene-editing techniques to develop next-generation therapeutics for multiple diseases using Precigen’s engineered cell and gene platforms
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●● companies3. Investors and private equity firms in Life Sciences Immunotherapeutic Vaccine Platforms sector
3.1 - Buyout funds in the Life Sciences Immunotherapeutic Vaccine Platforms sector
2.2 - Strategic buyer groups for Life Sciences Immunotherapeutic Vaccine Platforms sector
4 - Top valuation comps for Life Sciences Immunotherapeutic Vaccine Platforms companies
4.2 - Public trading comparable groups for Life Sciences Immunotherapeutic Vaccine Platforms sector
Valuation benchmark group 1: Platform Biotech and Therapeutics Companies
argenx
- Enterprise value: $●●●m
- Market Cap: $●●●m
- EV/Revenue: ●.●x
- EV/EBITDA: ●●.●x
- Description: Provider of antibody-based therapies focusing on treating severe autoimmune diseases, utilizing an innovative immunology platform to develop differentiated medicinal products for global markets.
- Key Products:
- Efgartigimod: An antibody therapy for immune disorders, improving symptom control in patients
- VYVGART: A first-in-class neonatal Fc receptor blocker for managing autoimmune conditions
- Immunology Innovation Program: Collaborates to accelerate novel target discovery and therapy development
- Clinical Trials: Executes global studies to validate efficacy and safety of therapeutic candidates
- Patient Support Services: Offers resources and guidance for patients using their therapies.