Orthopedic Bone Regeneration Devices sector
Strategic acquirers, private equity (buyout funds and growth funds) firms, and valuation benchmarks for Orthopedic Bone Regeneration Devices
1.1 - About Orthopedic Bone Regeneration Devices sector
Companies in Orthopedic Bone Regeneration Devices engineer biomaterial implants and combination devices that stimulate new bone formation and support structural repair. They serve orthopedic, spine, and craniofacial procedures by providing alternatives to autograft harvest, accelerating healing, and improving fusion success. These vendors design osteoconductive and osteoinductive solutions that rebuild defects after trauma, reconstruction, dental implant preparation, and revision surgeries, while aiming to reduce complications and surgical time.
Typical offerings span synthetic calcium phosphate grafts and hydroxyapatite/β‑TCP matrices, demineralized bone matrix allografts, bioresorbable polymer scaffolds, and carriers that deliver osteoinductive proteins such as BMP in drug‑device combinations. Companies also provide injectable putties and cements with proprietary mixing and delivery systems, 3D‑printed patient‑specific grafts and spinal cages, osteoconductive surface coatings for implants, and barrier membranes for guided bone regeneration in oral and maxillofacial use cases.
Primary customers include hospital systems and ambulatory surgery centers focused on orthopedics and spine, oral and maxillofacial and dental implant clinics, and trauma and reconstructive surgeons. Outcomes typically include higher fusion rates and faster time‑to‑union, reduced donor‑site morbidity by minimizing autograft harvest, lower revision and infection risk, and improved operative efficiency through standardized delivery systems and ready‑to‑use graft formats.
2. Buyers in the Orthopedic Bone Regeneration Devices sector
2.1 Top strategic acquirers of Orthopedic Bone Regeneration Devices companies
MiMedx
- Description: Provider of regenerative biologics derived from human placental tissues, developing, manufacturing and marketing amniotic membranes, umbilical cords, placental ECM and amniotic fluid products that modulate inflammation, reduce scar tissue and accelerate healing across wound care, surgical, orthopedic and other healthcare sectors.
- Key Products:
- Amniotic Membranes: Bioengineered tissue allografts processed via proprietary PURION method, delivering extracellular matrix components to modulate inflammation, reduce scarring and accelerate wound healing
- Umbilical Cords: Purified umbilical cord allografts providing structural matrix rich in growth factors to support tissue regeneration in orthopedic and surgical applications
- Placental ECM: Dehydrated placental extracellular matrix scaffolds offering key healing elements to repair damaged tissues, enhance cell infiltration and promote regenerative healing responses
- Amniotic Fluid: Allograft fluid containing cytokines and growth factors applied to damaged or diseased areas to reduce inflammation and stimulate cellular repair processes
- Company type: Private company
- Employees: ●●●●●
- Total funding raised: $●●●m
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2.2 - Strategic buyer groups for Orthopedic Bone Regeneration Devices sector
M&A buyer group 1: Orthopedics
Zimmer Biomet
- Type: N/A
- Employees: ●●●●●
- Description: Provider of medical technology solutions specializing in orthopaedics, offering implants and integrated digital-robotic platforms that leverage data, analytics and AI to maximize patient mobility, alleviate pain and improve quality of life worldwide.
- Key Products:
- ROSA Robotics Platform: Orthopedic surgical robotics system integrating navigation and semi/fully autonomous capabilities, giving surgeons flexible, precise tools for smarter personalized joint procedures
- The Personalized Knee: Patient-specific knee implant solution using individualized data to restore mobility, reduce pain and accelerate return to daily activities
- SternaLock Blu: Rigid sternal plate fixation device providing superior post-cardiac surgery stability, delivering 2.6-times higher healing rates at three months and 80% healing at six months
- Integrated Digital & Robotic Technology Suite: Data-driven digital platforms and AI-enabled robotics that enhance surgical precision, optimize outcomes and streamline orthopedic workflows across 100+ country operations.
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●● companies3. Investors and private equity firms in Orthopedic Bone Regeneration Devices sector
3.1 - Buyout funds in the Orthopedic Bone Regeneration Devices sector
2.2 - Strategic buyer groups for Orthopedic Bone Regeneration Devices sector
4 - Top valuation comps for Orthopedic Bone Regeneration Devices companies
4.2 - Public trading comparable groups for Orthopedic Bone Regeneration Devices sector
Valuation benchmark group 1: Orthopedic Implant Manufacturing Companies
Stryker
- Enterprise value: $●●●m
- Market Cap: $●●●m
- EV/Revenue: ●.●x
- EV/EBITDA: ●●.●x
- Description: Provider of medical technologies for improving patient and healthcare outcomes in MedSurg, neurotechnology, and orthopaedics. Offers innovative products and services such as surgical equipment, neurotechnology solutions, and orthopaedic implants, driven by a commitment to enhancing healthcare through quality and innovation.
- Key Products:
- Medical and Surgical Equipment: Advanced tools for surgical procedures
- Orthopaedic Implants: Solutions for bone fractures and joint replacements
- Neurotechnology Devices: Innovative products for neurological treatments
- Spine Surgery Systems: Equipment for spinal surgeries
- Reprocessing Services: Sustainable solutions for single-use medical devices.