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Valuation Trading Multiples & Precedent Transactions: Biopharma Research Tools and CDMOs

Valuation benchmarks for Biopharma Research Tools and CDMOs. Access public trading comps, EV/EBITDA acquisition multiples, and private market data for pitch books and valuation analysis.

1.1 - Biopharma Research Tools and CDMOs Market Context & Valuation Drivers

This public trading comparables group comprises biopharma service providers and tools vendors that enable discovery, development, and manufacturing of biologics and gene therapies. Business models span outsourced CRO/CDMO services and sale of critical bioprocess equipment, consumables, and analytics. They are comparable for valuation because revenues are tied to pipeline progression, cGMP capacity, and recurring supply contracts, with specialized know-how and regulatory compliance differentiating scale and margins.

Typical capabilities include integrated drug discovery platforms from target identification through lead optimization; CMC development for biologics and bioconjugates; cGMP manufacturing of drug substance and drug product with fill-finish and lyophilization; development of ADCs and novel bioconjugates; gene therapy vector and mRNA technologies; bioprocess hardware such as TFF and chromatography systems; affinity resins and in-process analytics; and supply of high-purity chemicals, reagents, and QC testing solutions.

Primary customers include global biopharma sponsors, emerging biotech and cell-gene therapy developers, and diagnostics/IVD manufacturers, as well as research laboratories. Valuation benchmarks emphasize revenue growth, backlog and book-to-bill, gross margin profile across services versus consumables, capacity utilization and expansion, and customer retention through long-term supply agreements. Scale, regulatory track record, and commercial program exposure drive durability and pricing power.

2. Valuation Analysis: Public Trading Comps & Multiples for Biopharma Research Tools and CDMOs companies

2.1 - Public Peer Groups & Median Valuation Multiples for Biopharma Research Tools and CDMOs sector

Description: This public trading comparables group comprises biopharma service providers and tools vendors that enable discovery, development, and manufacturing of biologics and gene therapies. Business models span outsourced CRO/CDMO services and sale of critical bioprocess equipment, consumables, and analytics. They are comparable for valuation because revenues are tied to pipeline progression, cGMP capacity, and recurring supply contracts, with specialized know-how and regulatory compliance differentiating scale and margins.
Pharmaron Beijing logo

Pharmaron Beijing

Website β€’ HQ: China
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of comprehensive research, development, and manufacturing services for the life sciences industry, encompassing drug discovery, preclinical, clinical, and commercialization stages across small molecules, biologics, and cell and gene therapy (CGT) products.
  • Key Products:
  • Chemistry, Manufacturing & Controls: Comprehensive service capabilities throughout drug discovery, preclinical, clinical development, and commercialization for small molecules, biologics, and CGT products
  • Pharmaron Biologics: Drug product manufacturing, including liquid, lyophilized vials, and pre-filled syringes, offering flexible solutions
  • Small Molecule Drug Product: Innovative and cost-effective solutions for drug development, covering a wide range of finished dosage forms including oral solid dosage forms
  • Integrated Drug Discovery Services: Leads projects from hit identification to candidate selection
  • Clinical Development: A broad spectrum of services for US clinical development processes.
Vazyme Biotech logo

Vazyme Biotech

Website β€’ HQ: China
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of biotechnology solutions specializing in the design, manufacture, and application of bioactive proteins and compounds. The company focuses on innovative enzyme-based solutions for clinical and molecular diagnostics, among other applications.
  • Key Products:
  • COVID-19 Solution: Comprehensive assay and diagnostic solutions for COVID-19 testing, including qPCR kits and antibodies
  • Molecular Biology Solutions: Offering reagents for PCR, qPCR, and NGS applications, catering to research and diagnostic needs
  • Custom Oligos: Providing custom oligonucleotide synthesis services with a focus on high-performance and precision
  • Enzyme Technologies: Development and manufacturing of enzyme solutions for diverse biological applications
  • Reagent Kits: Producing high-quality reagent kits for DNA and RNA extraction and sequencing.
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Revenue growth
Median
15.7%
2025E
16.0%
2026E
EBITDA margin
Median
28.2%
2025E
28.6%
2026E
Cash EBITDA margin
Median
27.6%
2025E
28.0%
2026E
EV/Revenue
Median
8.4x
2025E
6.8x
2026E
EV/EBITDA
Median
28.9x
2025E
24.4x
2026E
EV/Cash EBITDA
Median
29.0x
2025E
25.5x
2026E
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2.3 - Precedent M&A Transactions & Implied Enterprise Values for the Biopharma Research Tools and CDMOs secto

Selected M&A transactions

Date Target Description Buyer(s) Relevance EV EV/Revenue EV/EBITDA
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3. Potential Strategic Acquirers for Biopharma Research Tools and CDMOs

3.1 Top Strategic Buyers in Biopharma Research Tools and CDMOs

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3.2 - Strategic Buyer Groups & Adjacent Industry and Verticals to the Biopharma Research Tools and CDMOs sector

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Buyer group 1: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 2: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 3: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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4. Financial Sponsors & Private Equity in Biopharma Research Tools and CDMOs

4.1 - Buyout Funds active in Biopharma Research Tools and CDMOs

Buyout Funds investing in Biopharma Research Tools and CDMOs companies

50+ funds
Description: Buyout funds focused on Biopharma Research Tools and CDMOs companies globally.

4.2 - 4.2 - Growth Capital & Late-Stage Investorsin Biopharma Research Tools and CDMOs sector

Growth Equity Funds in Biopharma Research Tools and CDMOs companies

40+ funds
Description: Growth equity funds focused on Biopharma Research Tools and CDMOs companies globally.
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Valuation FAQ: Biopharma Research Tools and CDMOs

What is the current median EV/Revenue multiple for Biopharma Research Tools and CDMOs?

Based on our index of public trading comparables, the median Enterprise Value to Revenue (EV/Rev) multiple for the Biopharma Research Tools and CDMOs sector is currently ●.●x. High-growth peers in the top quartile are trading at ●●.●x. View full data.

What is the average EV/EBITDA multiple for companies in this sector?

Profitable companies in the Biopharma Research Tools and CDMOs sector trade at a median EV/EBITDA multiple of ●●.●x. This represents a change vs the 5-year historical average. Our platform tracks EBITDA multiples for Biopharma Research Tools and CDMOs and other key peer groups.

How have valuation multiples for Biopharma Research Tools and CDMOs trended over the last 5 years?

Valuations have adjusted since 2021. The sector saw peak multiples of ●●.●x EV/Revenue, settling to a 5-year average of ●.●x today. Access our Historical Trends chart for granular monthly data.

What are recent M&A transaction multiples in the Biopharma Research Tools and CDMOs space?

Recent precedent transactions indicate implied enterprise values ranging from ●.●x to ●●.●x Revenue. Private market deals often trade at a liquidity discount compared to public peers. Unlock the full list of precedent transactions.

Which public companies are used as trading comps for Biopharma Research Tools and CDMOs?

The primary trading comparable group includes Biopharma Research Tools and CDMOs. Key constituents used for benchmarking include large-cap leaders and specialized mid-cap players. See the full list of companies in the Public Trading Comps section.

How do I value a private company in the Biopharma Research Tools and CDMOs sector?

Valuing a private Biopharma Research Tools and CDMOs company typically involves applying current EV/Revenue and EV/EBITDA multiples from public peers to the private company's financial metrics. A discount for lack of marketability (DLOM) of 20-30% is often applied. Our private company valuation database provides the exact multiples needed for this calculation.

What are the Biopharma Research Tools and CDMOs industry valuation multiples for 2025?

For 2025, the Biopharma Research Tools and CDMOs industry is trading at a median EV/Revenue multiple of ●.●x. This reflects current market sentiment, interest rates, and growth expectations. Access our platform to see how these multiples have changed from 2024 to 2025.

What is the difference between trading comps and transaction multiples for Biopharma Research Tools and CDMOs?

Trading comps look at how public markets value similar companies today, while transaction multiples (or precedent transactions) look at the price paid in past M&A deals. Transaction multiples often include a "control premium," typically resulting in higher valuations than trading comps. Our database tracks both trading multiples and M&A transaction multiples.

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