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Valuation Trading Multiples & Precedent Transactions: Genomics Tools and Precision Diagnostics Companies

Valuation benchmarks for Genomics Tools and Precision Diagnostics Companies. Access public trading comps, EV/EBITDA acquisition multiples, and private market data for pitch books and valuation analysis.

1.1 - Genomics Tools and Precision Diagnostics Companies Market Context & Valuation Drivers

Companies in this public trading comparables group develop and commercialize genomics tools and precision oncology diagnostics. Business models span CLIA/FDA-approved liquid biopsy assays, comprehensive genomic profiling, synthetic DNA manufacturing, and outsourced sequencing and biobanking services. They are comparable as valuation benchmarks given shared exposure to NGS workflows, recurring consumables and services revenue, payer/provider adoption cycles, and biopharma research demand.

Typical capabilities include liquid biopsy testing for mutation detection and MRD monitoring, tumor-informed assays and comprehensive genomic profiling, high-throughput gene synthesis and oligonucleotide production, targeted NGS enrichment kits, end-to-end sequencing and bioinformatics, cryogenic biobanking and sample tracking, and laboratory automation for sample management. Revenue models combine per-test fees, project-based services, reagent and consumables sales, and long-term storage contracts. Many also offer informatics subscriptions, secure data reporting portals, and integration with clinical decision-support systems.

Primary customers include oncology providers and health systems adopting precision diagnostics, biopharma and biotech R&D teams, and academic research institutions. Key valuation drivers are revenue growth from test volumes and consumables utilization, gross margin expansion via scale and mix, recurring services and storage contracts, and payer coverage and reimbursement milestones. Metrics such as ASPs, sample throughput, customer retention, and backlog provide comparable benchmarks across public trading comps.

2. Valuation Analysis: Public Trading Comps & Multiples for Genomics Tools and Precision Diagnostics Companies companies

2.1 - Public Peer Groups & Median Valuation Multiples for Genomics Tools and Precision Diagnostics Companies sector

Description: Companies in this public trading comparables group develop and commercialize genomics tools and precision oncology diagnostics. Business models span CLIA/FDA-approved liquid biopsy assays, comprehensive genomic profiling, synthetic DNA manufacturing, and outsourced sequencing and biobanking services. They are comparable as valuation benchmarks given shared exposure to NGS workflows, recurring consumables and services revenue, payer/provider adoption cycles, and biopharma research demand.
Guardant Health logo

Guardant Health

Website β€’ HQ: United States
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of blood and tissue tests, data sets, and analytics with a focus on the treatment and management of cancer through precision oncology and advanced research platforms.
  • Key Products:
  • Guardant360 CDx Test: FDA-approved liquid biopsy test for identifying patients with specific gene mutations to guide treatment decisions
  • GuardantOMNI: Liquid biopsy test for comprehensive genomic profiling of tumors in cancer patients
  • Shield Test: Blood-based test for colorectal cancer screening
  • Guardant Reveal: Blood-only liquid biopsy test for detecting residual and recurrent colorectal cancer
  • GuardantINFINITY: High-definition liquid biopsy test for advanced-stage solid tumors.
Twist Bioscience logo

Twist Bioscience

Website β€’ HQ: United States
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of synthetic DNA and genomics products using a proprietary semiconductor-based platform to offer high-throughput DNA synthesis for applications in therapeutics, diagnostics, agriculture, chemicals, and data storage.
  • Key Products:
  • Gene synthesis: High-throughput silicon-based platform to produce custom genes rapidly and accurately
  • Oligo pools: Large-scale production of oligonucleotides for high-throughput screening
  • NGS target enrichment: Tools for targeted next-generation sequencing
  • Variant libraries: Diverse libraries for accelerated drug discovery
  • Biopharma solutions: Antibody discovery and optimization services.
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Revenue growth
Median
15.7%
2025E
16.0%
2026E
EBITDA margin
Median
28.2%
2025E
28.6%
2026E
Cash EBITDA margin
Median
27.6%
2025E
28.0%
2026E
EV/Revenue
Median
8.4x
2025E
6.8x
2026E
EV/EBITDA
Median
28.9x
2025E
24.4x
2026E
EV/Cash EBITDA
Median
29.0x
2025E
25.5x
2026E
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2.3 - Precedent M&A Transactions & Implied Enterprise Values for the Genomics Tools and Precision Diagnostics Companies secto

Selected M&A transactions

Date Target Description Buyer(s) Relevance EV EV/Revenue EV/EBITDA
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3. Potential Strategic Acquirers for Genomics Tools and Precision Diagnostics Companies

3.1 Top Strategic Buyers in Genomics Tools and Precision Diagnostics Companies

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3.2 - Strategic Buyer Groups & Adjacent Industry and Verticals to the Genomics Tools and Precision Diagnostics Companies sector

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Buyer group 1: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 2: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 3: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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4. Financial Sponsors & Private Equity in Genomics Tools and Precision Diagnostics Companies

4.1 - Buyout Funds active in Genomics Tools and Precision Diagnostics Companies

Buyout Funds investing in Genomics Tools and Precision Diagnostics Companies companies

50+ funds
Description: Buyout funds focused on Genomics Tools and Precision Diagnostics Companies companies globally.

4.2 - 4.2 - Growth Capital & Late-Stage Investorsin Genomics Tools and Precision Diagnostics Companies sector

Growth Equity Funds in Genomics Tools and Precision Diagnostics Companies companies

40+ funds
Description: Growth equity funds focused on Genomics Tools and Precision Diagnostics Companies companies globally.
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Valuation FAQ: Genomics Tools and Precision Diagnostics Companies

What is the current median EV/Revenue multiple for Genomics Tools and Precision Diagnostics Companies?

Based on our index of public trading comparables, the median Enterprise Value to Revenue (EV/Rev) multiple for the Genomics Tools and Precision Diagnostics Companies sector is currently ●.●x. High-growth peers in the top quartile are trading at ●●.●x. View full data.

What is the average EV/EBITDA multiple for companies in this sector?

Profitable companies in the Genomics Tools and Precision Diagnostics Companies sector trade at a median EV/EBITDA multiple of ●●.●x. This represents a change vs the 5-year historical average. Our platform tracks EBITDA multiples for Genomics Tools and Precision Diagnostics Companies and other key peer groups.

How have valuation multiples for Genomics Tools and Precision Diagnostics Companies trended over the last 5 years?

Valuations have adjusted since 2021. The sector saw peak multiples of ●●.●x EV/Revenue, settling to a 5-year average of ●.●x today. Access our Historical Trends chart for granular monthly data.

What are recent M&A transaction multiples in the Genomics Tools and Precision Diagnostics Companies space?

Recent precedent transactions indicate implied enterprise values ranging from ●.●x to ●●.●x Revenue. Private market deals often trade at a liquidity discount compared to public peers. Unlock the full list of precedent transactions.

Which public companies are used as trading comps for Genomics Tools and Precision Diagnostics Companies?

The primary trading comparable group includes Genomics Tools and Precision Diagnostics Companies. Key constituents used for benchmarking include large-cap leaders and specialized mid-cap players. See the full list of companies in the Public Trading Comps section.

How do I value a private company in the Genomics Tools and Precision Diagnostics Companies sector?

Valuing a private Genomics Tools and Precision Diagnostics Companies company typically involves applying current EV/Revenue and EV/EBITDA multiples from public peers to the private company's financial metrics. A discount for lack of marketability (DLOM) of 20-30% is often applied. Our private company valuation database provides the exact multiples needed for this calculation.

What are the Genomics Tools and Precision Diagnostics Companies industry valuation multiples for 2025?

For 2025, the Genomics Tools and Precision Diagnostics Companies industry is trading at a median EV/Revenue multiple of ●.●x. This reflects current market sentiment, interest rates, and growth expectations. Access our platform to see how these multiples have changed from 2024 to 2025.

What is the difference between trading comps and transaction multiples for Genomics Tools and Precision Diagnostics Companies?

Trading comps look at how public markets value similar companies today, while transaction multiples (or precedent transactions) look at the price paid in past M&A deals. Transaction multiples often include a "control premium," typically resulting in higher valuations than trading comps. Our database tracks both trading multiples and M&A transaction multiples.

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