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Valuation Trading Multiples & Precedent Transactions: Monoclonal Antibody Drug Developers

Valuation benchmarks for Monoclonal Antibody Drug Developers. Access public trading comps, EV/EBITDA acquisition multiples, and private market data for pitch books and valuation analysis.

1.1 - Monoclonal Antibody Drug Developers Market Context & Valuation Drivers

Companies in this trading comparables group are public biopharmaceutical businesses that research, develop, manufacture, and commercialize therapeutic monoclonal antibodies and related biologics. They pursue oncology, immunology, and rare disease indications, generating revenue from marketed biologics, biosimilars, and licensing. They are comparable for valuation because they share R&D‑intensive models, cGMP biologics manufacturing, similar regulatory pathways, and pipeline risk/return profiles that define benchmarks in antibody therapeutics.

Typical capabilities include discovery and optimization of therapeutic monoclonal antibodies, development of antibody‑drug conjugates, and advancement of biosimilar antibodies to established reference products. Companies operate cGMP biologics manufacturing, scale cell culture production, and run preclinical and multi‑phase clinical trials. Many also produce recombinant proteins and vaccines, offer technology transfer or out‑licensing, and manage commercialization, market access, and pharmacovigilance for approved biologics across oncology, immunology, and hematology indications.

Primary customers include hospitals and health systems, specialty clinics and infusion centers, national procurement agencies, and biopharma partners for licensing or co‑development. Valuation drivers typically center on revenue growth from product launches, biologics gross margins and manufacturing yields, timing of clinical and regulatory milestones, market penetration and reimbursement durability, and pipeline quality measured by risk‑adjusted NPV and cash runway relative to R&D intensity.

2. Valuation Analysis: Public Trading Comps & Multiples for Monoclonal Antibody Drug Developers companies

2.1 - Public Peer Groups & Median Valuation Multiples for Monoclonal Antibody Drug Developers sector

Description: Companies in this trading comparables group are public biopharmaceutical businesses that research, develop, manufacture, and commercialize therapeutic monoclonal antibodies and related biologics. They pursue oncology, immunology, and rare disease indications, generating revenue from marketed biologics, biosimilars, and licensing. They are comparable for valuation because they share R&D‑intensive models, cGMP biologics manufacturing, similar regulatory pathways, and pipeline risk/return profiles that define benchmarks in antibody therapeutics.
Hualan Biological Engineering logo

Hualan Biological Engineering

Website β€’ HQ: China
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of research, development, production, and commercialization of human blood products, vaccines, monoclonal antibody, and genetic recombination biologics, achieving significant innovation and market impact in China's biopharmaceutical industry.
  • Key Products:
  • Plasma Products: High-quality human blood plasma for medical use
  • Viral Vaccines: Development and production of vaccines for viral diseases
  • Bacterial Vaccines: Production of vaccines for bacterial infections
  • Monoclonal Antibodies: Research and development of therapeutic monoclonal antibodies
  • Genetic Recombination Biologics: Production and commercialization of genetically engineered biologics
Sinocelltech Group logo

Sinocelltech Group

Website β€’ HQ: China
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of biotechnology solutions specializing in the development and production of recombinant proteins, monoclonal antibodies, and vaccines with applications in various therapeutic areas including oncology, autoimmune diseases, and infectious diseases.
  • Key Products:
  • Recombinant Proteins: Biopharmaceutical products for therapeutic interventions across various diseases
  • Monoclonal Antibodies: Targeted therapies for autoimmune and oncological conditions
  • Vaccines: Provides immunity against infectious agents
  • Ripertamab: Anti-CD20 monoclonal antibody approved by China's NMPA
  • SCT200: Humanized anti-EGFR monoclonal antibody for cancer treatment
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Revenue growth
Median
15.7%
2025E
16.0%
2026E
EBITDA margin
Median
28.2%
2025E
28.6%
2026E
Cash EBITDA margin
Median
27.6%
2025E
28.0%
2026E
EV/Revenue
Median
8.4x
2025E
6.8x
2026E
EV/EBITDA
Median
28.9x
2025E
24.4x
2026E
EV/Cash EBITDA
Median
29.0x
2025E
25.5x
2026E
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2.3 - Precedent M&A Transactions & Implied Enterprise Values for the Monoclonal Antibody Drug Developers secto

Selected M&A transactions

Date Target Description Buyer(s) Relevance EV EV/Revenue EV/EBITDA
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3. Potential Strategic Acquirers for Monoclonal Antibody Drug Developers

3.1 Top Strategic Buyers in Monoclonal Antibody Drug Developers

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3.2 - Strategic Buyer Groups & Adjacent Industry and Verticals to the Monoclonal Antibody Drug Developers sector

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Buyer group 1: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 2: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 3: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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4. Financial Sponsors & Private Equity in Monoclonal Antibody Drug Developers

4.1 - Buyout Funds active in Monoclonal Antibody Drug Developers

Buyout Funds investing in Monoclonal Antibody Drug Developers companies

50+ funds
Description: Buyout funds focused on Monoclonal Antibody Drug Developers companies globally.

4.2 - 4.2 - Growth Capital & Late-Stage Investorsin Monoclonal Antibody Drug Developers sector

Growth Equity Funds in Monoclonal Antibody Drug Developers companies

40+ funds
Description: Growth equity funds focused on Monoclonal Antibody Drug Developers companies globally.
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Valuation FAQ: Monoclonal Antibody Drug Developers

What is the current median EV/Revenue multiple for Monoclonal Antibody Drug Developers?

Based on our index of public trading comparables, the median Enterprise Value to Revenue (EV/Rev) multiple for the Monoclonal Antibody Drug Developers sector is currently ●.●x. High-growth peers in the top quartile are trading at ●●.●x. View full data.

What is the average EV/EBITDA multiple for companies in this sector?

Profitable companies in the Monoclonal Antibody Drug Developers sector trade at a median EV/EBITDA multiple of ●●.●x. This represents a change vs the 5-year historical average. Our platform tracks EBITDA multiples for Monoclonal Antibody Drug Developers and other key peer groups.

How have valuation multiples for Monoclonal Antibody Drug Developers trended over the last 5 years?

Valuations have adjusted since 2021. The sector saw peak multiples of ●●.●x EV/Revenue, settling to a 5-year average of ●.●x today. Access our Historical Trends chart for granular monthly data.

What are recent M&A transaction multiples in the Monoclonal Antibody Drug Developers space?

Recent precedent transactions indicate implied enterprise values ranging from ●.●x to ●●.●x Revenue. Private market deals often trade at a liquidity discount compared to public peers. Unlock the full list of precedent transactions.

Which public companies are used as trading comps for Monoclonal Antibody Drug Developers?

The primary trading comparable group includes Monoclonal Antibody Drug Developers. Key constituents used for benchmarking include large-cap leaders and specialized mid-cap players. See the full list of companies in the Public Trading Comps section.

How do I value a private company in the Monoclonal Antibody Drug Developers sector?

Valuing a private Monoclonal Antibody Drug Developers company typically involves applying current EV/Revenue and EV/EBITDA multiples from public peers to the private company's financial metrics. A discount for lack of marketability (DLOM) of 20-30% is often applied. Our private company valuation database provides the exact multiples needed for this calculation.

What are the Monoclonal Antibody Drug Developers industry valuation multiples for 2025?

For 2025, the Monoclonal Antibody Drug Developers industry is trading at a median EV/Revenue multiple of ●.●x. This reflects current market sentiment, interest rates, and growth expectations. Access our platform to see how these multiples have changed from 2024 to 2025.

What is the difference between trading comps and transaction multiples for Monoclonal Antibody Drug Developers?

Trading comps look at how public markets value similar companies today, while transaction multiples (or precedent transactions) look at the price paid in past M&A deals. Transaction multiples often include a "control premium," typically resulting in higher valuations than trading comps. Our database tracks both trading multiples and M&A transaction multiples.

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