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Valuation Trading Multiples & Precedent Transactions: Prophylactic Vaccine Manufacturing Companies

Valuation benchmarks for Prophylactic Vaccine Manufacturing Companies. Access public trading comps, EV/EBITDA acquisition multiples, and private market data for pitch books and valuation analysis.

1.1 - Prophylactic Vaccine Manufacturing Companies Market Context & Valuation Drivers

Companies in this trading comparable group are public manufacturers and suppliers of human prophylactic vaccines. They integrate R&D, GMP biologics production, and cold-chain distribution to deliver routine immunizations across multiple infectious disease categories. Revenue is driven by dose volumes and average selling prices through national tenders and commercial channels. They are comparable for valuation benchmarks given similar product portfolios, regulatory requirements, capital intensity, and procurement dynamics shaping growth and margin profiles.

These businesses develop viral and bacterial vaccines spanning pneumococcal conjugate, HPV, influenza, meningococcal, rabies, and rotavirus. Core capabilities include antigen scale-up and conjugation chemistry, adjuvant formulation, sterile fill‑finish, quality control, and batch release under GMP. They run clinical trials and regulatory submissions, and operate warehousing, customs clearance, and cold‑chain logistics for broad distribution, with some diversification into plasma products, recombinant proteins, and monoclonal antibodies to leverage manufacturing platforms and improve utilization.

Primary customers include national immunization programs and public health agencies, hospitals and clinics, and vaccine distributors/pharmacies. Key valuation drivers include dose volumes and tender wins, average selling prices, revenue growth across geographies, gross margin from product mix and manufacturing yields, capacity utilization of fill‑finish lines, and pipeline advancement/approvals. Analysts also monitor contract duration, seasonal demand profiles, and cold‑chain distribution efficiency as indicators of predictability and scalability.

2. Valuation Analysis: Public Trading Comps & Multiples for Prophylactic Vaccine Manufacturing Companies companies

2.1 - Public Peer Groups & Median Valuation Multiples for Prophylactic Vaccine Manufacturing Companies sector

Description: Companies in this trading comparable group are public manufacturers and suppliers of human prophylactic vaccines. They integrate R&D, GMP biologics production, and cold-chain distribution to deliver routine immunizations across multiple infectious disease categories. Revenue is driven by dose volumes and average selling prices through national tenders and commercial channels. They are comparable for valuation benchmarks given similar product portfolios, regulatory requirements, capital intensity, and procurement dynamics shaping growth and margin profiles.
Chongqing Zhifei logo

Chongqing Zhifei

Website β€’ HQ: China
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of warehousing, customs clearance, and batch release services for imported goods through their airport facilities; also offers logistics, distribution, and product promotion services.
  • Key Products:
  • Warehousing: Offers storage solutions for various goods at their facilities
  • Customs Clearance: Facilitates regulatory clearance for imported products
  • Batch Release: Manages scheduled release of products
  • Logistics & Distribution: Provides comprehensive logistics and distribution services
  • Product Promotion: Offers promotional services to enhance product visibility and market reach.
Hualan Biological Engineering logo

Hualan Biological Engineering

Website β€’ HQ: China
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of research, development, production, and commercialization of human blood products, vaccines, monoclonal antibody, and genetic recombination biologics, achieving significant innovation and market impact in China's biopharmaceutical industry.
  • Key Products:
  • Plasma Products: High-quality human blood plasma for medical use
  • Viral Vaccines: Development and production of vaccines for viral diseases
  • Bacterial Vaccines: Production of vaccines for bacterial infections
  • Monoclonal Antibodies: Research and development of therapeutic monoclonal antibodies
  • Genetic Recombination Biologics: Production and commercialization of genetically engineered biologics
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Revenue growth
Median
15.7%
2025E
16.0%
2026E
EBITDA margin
Median
28.2%
2025E
28.6%
2026E
Cash EBITDA margin
Median
27.6%
2025E
28.0%
2026E
EV/Revenue
Median
8.4x
2025E
6.8x
2026E
EV/EBITDA
Median
28.9x
2025E
24.4x
2026E
EV/Cash EBITDA
Median
29.0x
2025E
25.5x
2026E
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2.3 - Precedent M&A Transactions & Implied Enterprise Values for the Prophylactic Vaccine Manufacturing Companies secto

Selected M&A transactions

Date Target Description Buyer(s) Relevance EV EV/Revenue EV/EBITDA
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3. Potential Strategic Acquirers for Prophylactic Vaccine Manufacturing Companies

3.1 Top Strategic Buyers in Prophylactic Vaccine Manufacturing Companies

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3.2 - Strategic Buyer Groups & Adjacent Industry and Verticals to the Prophylactic Vaccine Manufacturing Companies sector

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Buyer group 1: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 2: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 3: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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4. Financial Sponsors & Private Equity in Prophylactic Vaccine Manufacturing Companies

4.1 - Buyout Funds active in Prophylactic Vaccine Manufacturing Companies

Buyout Funds investing in Prophylactic Vaccine Manufacturing Companies companies

50+ funds
Description: Buyout funds focused on Prophylactic Vaccine Manufacturing Companies companies globally.

4.2 - 4.2 - Growth Capital & Late-Stage Investorsin Prophylactic Vaccine Manufacturing Companies sector

Growth Equity Funds in Prophylactic Vaccine Manufacturing Companies companies

40+ funds
Description: Growth equity funds focused on Prophylactic Vaccine Manufacturing Companies companies globally.
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Valuation FAQ: Prophylactic Vaccine Manufacturing Companies

What is the current median EV/Revenue multiple for Prophylactic Vaccine Manufacturing Companies?

Based on our index of public trading comparables, the median Enterprise Value to Revenue (EV/Rev) multiple for the Prophylactic Vaccine Manufacturing Companies sector is currently ●.●x. High-growth peers in the top quartile are trading at ●●.●x. View full data.

What is the average EV/EBITDA multiple for companies in this sector?

Profitable companies in the Prophylactic Vaccine Manufacturing Companies sector trade at a median EV/EBITDA multiple of ●●.●x. This represents a change vs the 5-year historical average. Our platform tracks EBITDA multiples for Prophylactic Vaccine Manufacturing Companies and other key peer groups.

How have valuation multiples for Prophylactic Vaccine Manufacturing Companies trended over the last 5 years?

Valuations have adjusted since 2021. The sector saw peak multiples of ●●.●x EV/Revenue, settling to a 5-year average of ●.●x today. Access our Historical Trends chart for granular monthly data.

What are recent M&A transaction multiples in the Prophylactic Vaccine Manufacturing Companies space?

Recent precedent transactions indicate implied enterprise values ranging from ●.●x to ●●.●x Revenue. Private market deals often trade at a liquidity discount compared to public peers. Unlock the full list of precedent transactions.

Which public companies are used as trading comps for Prophylactic Vaccine Manufacturing Companies?

The primary trading comparable group includes Prophylactic Vaccine Manufacturing Companies. Key constituents used for benchmarking include large-cap leaders and specialized mid-cap players. See the full list of companies in the Public Trading Comps section.

How do I value a private company in the Prophylactic Vaccine Manufacturing Companies sector?

Valuing a private Prophylactic Vaccine Manufacturing Companies company typically involves applying current EV/Revenue and EV/EBITDA multiples from public peers to the private company's financial metrics. A discount for lack of marketability (DLOM) of 20-30% is often applied. Our private company valuation database provides the exact multiples needed for this calculation.

What are the Prophylactic Vaccine Manufacturing Companies industry valuation multiples for 2025?

For 2025, the Prophylactic Vaccine Manufacturing Companies industry is trading at a median EV/Revenue multiple of ●.●x. This reflects current market sentiment, interest rates, and growth expectations. Access our platform to see how these multiples have changed from 2024 to 2025.

What is the difference between trading comps and transaction multiples for Prophylactic Vaccine Manufacturing Companies?

Trading comps look at how public markets value similar companies today, while transaction multiples (or precedent transactions) look at the price paid in past M&A deals. Transaction multiples often include a "control premium," typically resulting in higher valuations than trading comps. Our database tracks both trading multiples and M&A transaction multiples.

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