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Valuation Trading Multiples & Precedent Transactions: RNA and Peptide Therapeutics Companies

Valuation benchmarks for RNA and Peptide Therapeutics Companies. Access public trading comps, EV/EBITDA acquisition multiples, and private market data for pitch books and valuation analysis.

1.1 - RNA and Peptide Therapeutics Companies Market Context & Valuation Drivers

Companies in this trading comparables group develop, manufacture, and commercialize RNA- and peptide-based therapeutics, alongside select small-molecule specialty drugs and related diagnostics. Business models span commercial-stage biopharma product sales, licensing and royalty agreements, and GMP peptide/oligonucleotide contract manufacturing. They are grouped together as valuation benchmarks due to shared modality focus, clinical and regulatory pathways, and revenue exposure to innovative oncology, neurology, immunology, and infectious disease treatments.

Typical capabilities include discovery and clinical development of antisense oligonucleotides and peptide therapeutics, commercial manufacturing of GMP peptide and oligonucleotide active pharmaceutical ingredients, scale-up and process development, regulatory submissions and post-marketing surveillance, and global commercialization through specialty salesforces and distribution partners. Many also provide molecular diagnostics and genetic testing services, out-licensing and co-development partnerships, and managed access programs across oncology, neurology, immunology, cardio-renal, and infectious disease indications.

Primary customers include hospital systems and healthcare providers prescribing specialty therapies, biopharma sponsors procuring peptide and oligonucleotide manufacturing, and diagnostic labs deploying molecular tests. Valuation drivers center on net sales growth of approved products, gross margin profile by product and services mix, pipeline advancement and regulatory approvals, capacity utilization for manufacturing operations, and durability of royalty streams and partnerships that sustain cash flow visibility.

2. Valuation Analysis: Public Trading Comps & Multiples for RNA and Peptide Therapeutics Companies companies

2.1 - Public Peer Groups & Median Valuation Multiples for RNA and Peptide Therapeutics Companies sector

Description: Companies in this trading comparables group develop, manufacture, and commercialize RNA- and peptide-based therapeutics, alongside select small-molecule specialty drugs and related diagnostics. Business models span commercial-stage biopharma product sales, licensing and royalty agreements, and GMP peptide/oligonucleotide contract manufacturing. They are grouped together as valuation benchmarks due to shared modality focus, clinical and regulatory pathways, and revenue exposure to innovative oncology, neurology, immunology, and infectious disease treatments.
Everest Medicines logo

Everest Medicines

Website HQ: China
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of innovative biopharmaceutical solutions focused on discovering, developing, manufacturing, and commercializing transformative pharmaceutical products and vaccines that address critical unmet medical needs in Greater China and other Asia-Pacific markets. With a portfolio that includes oncology, immunology, cardio-renal diseases, and infectious diseases therapies, the company integrates licensing, clinical development, and commercialization to deliver next-generation treatments.
  • Key Products:
  • Oncology Therapies: Cutting-edge treatments for various cancers
  • Immunology Treatments: Advanced therapies for autoimmune conditions
  • Cardio-renal Drugs: Innovative solutions for cardiovascular and renal diseases
  • Infectious Disease Medications: Next-generation treatments for bacterial and viral infections
  • Vaccine Production: Development and manufacturing of transformative vaccines.
Pharma Mar logo

Pharma Mar

Website HQ: Spain
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of biopharmaceutical solutions focused on researching, developing, and commercializing oncology treatments derived from marine sources, aimed at improving the lives of patients with serious illnesses.
  • Key Products:
  • Yondelis®: Treatment for advanced soft tissue sarcoma and ovarian cancer
  • Zepzelca®: Therapy for small-cell lung cancer
  • Aplidin®: Antiviral agent for treating COVID-19 and other viral infections
  • Molecular Diagnostics: Testing for infectious diseases, including COVID-19
  • Genetic Analysis: Services for genetic analysis and paternity testing.
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Revenue growth
Median
15.7%
2025E
16.0%
2026E
EBITDA margin
Median
28.2%
2025E
28.6%
2026E
Cash EBITDA margin
Median
27.6%
2025E
28.0%
2026E
EV/Revenue
Median
8.4x
2025E
6.8x
2026E
EV/EBITDA
Median
28.9x
2025E
24.4x
2026E
EV/Cash EBITDA
Median
29.0x
2025E
25.5x
2026E
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2.3 - Precedent M&A Transactions & Implied Enterprise Values for the RNA and Peptide Therapeutics Companies secto

Selected M&A transactions

Date Target Description Buyer(s) Relevance EV EV/Revenue EV/EBITDA
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3. Potential Strategic Acquirers for RNA and Peptide Therapeutics Companies

3.1 Top Strategic Buyers in RNA and Peptide Therapeutics Companies

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3.2 - Strategic Buyer Groups & Adjacent Industry and Verticals to the RNA and Peptide Therapeutics Companies sector

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Key Products: ████████, ████████, ████████, ████████
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Buyer group 2: ████████ ████████

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Key Products: ████████, ████████, ████████, ████████
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Buyer group 3: ████████ ████████

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Description: ████████ ████████ ████████ ████████ ████████ ████████ ████████ ████████ ████████ ████████
Key Products: ████████, ████████, ████████, ████████
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4. Financial Sponsors & Private Equity in RNA and Peptide Therapeutics Companies

4.1 - Buyout Funds active in RNA and Peptide Therapeutics Companies

Buyout Funds investing in RNA and Peptide Therapeutics Companies companies

50+ funds
Description: Buyout funds focused on RNA and Peptide Therapeutics Companies companies globally.

4.2 - 4.2 - Growth Capital & Late-Stage Investorsin RNA and Peptide Therapeutics Companies sector

Growth Equity Funds in RNA and Peptide Therapeutics Companies companies

40+ funds
Description: Growth equity funds focused on RNA and Peptide Therapeutics Companies companies globally.
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Valuation FAQ: RNA and Peptide Therapeutics Companies

What is the current median EV/Revenue multiple for RNA and Peptide Therapeutics Companies?

Based on our index of public trading comparables, the median Enterprise Value to Revenue (EV/Rev) multiple for the RNA and Peptide Therapeutics Companies sector is currently ●.●x. High-growth peers in the top quartile are trading at ●●.●x. View full data.

What is the average EV/EBITDA multiple for companies in this sector?

Profitable companies in the RNA and Peptide Therapeutics Companies sector trade at a median EV/EBITDA multiple of ●●.●x. This represents a change vs the 5-year historical average. Our platform tracks EBITDA multiples for RNA and Peptide Therapeutics Companies and other key peer groups.

How have valuation multiples for RNA and Peptide Therapeutics Companies trended over the last 5 years?

Valuations have adjusted since 2021. The sector saw peak multiples of ●●.●x EV/Revenue, settling to a 5-year average of ●.●x today. Access our Historical Trends chart for granular monthly data.

What are recent M&A transaction multiples in the RNA and Peptide Therapeutics Companies space?

Recent precedent transactions indicate implied enterprise values ranging from ●.●x to ●●.●x Revenue. Private market deals often trade at a liquidity discount compared to public peers. Unlock the full list of precedent transactions.

Which public companies are used as trading comps for RNA and Peptide Therapeutics Companies?

The primary trading comparable group includes RNA and Peptide Therapeutics Companies. Key constituents used for benchmarking include large-cap leaders and specialized mid-cap players. See the full list of companies in the Public Trading Comps section.

How do I value a private company in the RNA and Peptide Therapeutics Companies sector?

Valuing a private RNA and Peptide Therapeutics Companies company typically involves applying current EV/Revenue and EV/EBITDA multiples from public peers to the private company's financial metrics. A discount for lack of marketability (DLOM) of 20-30% is often applied. Our private company valuation database provides the exact multiples needed for this calculation.

What are the RNA and Peptide Therapeutics Companies industry valuation multiples for 2025?

For 2025, the RNA and Peptide Therapeutics Companies industry is trading at a median EV/Revenue multiple of ●.●x. This reflects current market sentiment, interest rates, and growth expectations. Access our platform to see how these multiples have changed from 2024 to 2025.

What is the difference between trading comps and transaction multiples for RNA and Peptide Therapeutics Companies?

Trading comps look at how public markets value similar companies today, while transaction multiples (or precedent transactions) look at the price paid in past M&A deals. Transaction multiples often include a "control premium," typically resulting in higher valuations than trading comps. Our database tracks both trading multiples and M&A transaction multiples.

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