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Valuation Trading Multiples & Precedent Transactions: Small-Molecule Pharmaceutical Manufacturing Companies

Valuation benchmarks for Small-Molecule Pharmaceutical Manufacturing Companies. Access public trading comps, EV/EBITDA acquisition multiples, and private market data for pitch books and valuation analysis.

1.1 - Small-Molecule Pharmaceutical Manufacturing Companies Market Context & Valuation Drivers

Companies in this group research, manufacture, and commercialize small-molecule therapeutics across branded specialty, generics, and sterile injectables. Many operate integrated platforms spanning formulation, cGMP production, and multi-channel distribution to hospitals and pharmacies. They are grouped as public trading comparables given similar regulatory exposure, product mix, and revenue models anchored in prescription drug sales, tender contracts, and OTC offerings, enabling consistent valuation benchmarks.

Typical capabilities include discovery and development of chemical entities, formulation and scale-up, regulatory submissions, and cGMP manufacturing for oral solids, liquids, and injectables. Companies offer sterile compounding, specialty injectables, anesthesia and critical-care drugs, oncology and immuno-inflammatory small molecules, ophthalmic and dermatology products, and OTC formulations. Many manage hospital tendering, pharmacovigilance, and global distribution, while pursuing licensing, co-development, and lifecycle management to extend indications and defend margins.

Primary customers include hospitals and health systems, retail and specialty pharmacies, government procurement agencies, and clinical practices. Valuation drivers typically include revenue growth by therapeutic area, gross margin mix between branded and generic portfolios, approval cadence and pipeline productivity, tender win rates and market share in key indications, and operating leverage from manufacturing scale and distribution reach, which impact cash generation and return on invested capital.

2. Valuation Analysis: Public Trading Comps & Multiples for Small-Molecule Pharmaceutical Manufacturing Companies companies

2.1 - Public Peer Groups & Median Valuation Multiples for Small-Molecule Pharmaceutical Manufacturing Companies sector

Description: Companies in this group research, manufacture, and commercialize small-molecule therapeutics across branded specialty, generics, and sterile injectables. Many operate integrated platforms spanning formulation, cGMP production, and multi-channel distribution to hospitals and pharmacies. They are grouped as public trading comparables given similar regulatory exposure, product mix, and revenue models anchored in prescription drug sales, tender contracts, and OTC offerings, enabling consistent valuation benchmarks.
Fagron logo

Fagron

Website β€’ HQ: Belgium
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of pharmaceutical compounding solutions and personalized medicine services, utilizing advanced technology to meet the specific needs of healthcare providers and patients globally.
  • Key Products:
  • Sterile compounding: Production of individual sterile medications with rigorous quality control
  • Custom formulations: Unique pharmaceutical preparations tailored to meet specific patient needs
  • Fagron TrichoConcept: Multifunctional compounding vehicles for alopecia treatment with patented TrichoTech technology
  • FagronLab Equipment: Advanced compounding tools and systems for pharmacies
  • Fagron Formulary: Comprehensive range of customizable formulas for pharmacists and prescribers.
Bausch Health logo

Bausch Health

Website β€’ HQ: Canada
  • Enterprise value: $●●●m
  • Market Cap: $●●●m
  • EV/Revenue: ●.●x
  • EV/EBITDA: ●●.●x
  • Description: Provider of pharmaceutical products in the fields of gastroenterology, hepatology, neurology, dermatology, and other healthcare sectors, focusing on enhancing health outcomes through diversified product offerings.
  • Key Products:
  • Eye Health Products: Comprehensive eye care solutions through Bausch + Lomb
  • Gastroenterology Medications: Treatments for digestive health issues
  • Neurology Devices: Solutions for neurological conditions
  • Dermatology Products: Skincare solutions addressing various conditions
  • Dental Products: Instruments and solutions for dental care.
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Revenue growth
Median
15.7%
2025E
16.0%
2026E
EBITDA margin
Median
28.2%
2025E
28.6%
2026E
Cash EBITDA margin
Median
27.6%
2025E
28.0%
2026E
EV/Revenue
Median
8.4x
2025E
6.8x
2026E
EV/EBITDA
Median
28.9x
2025E
24.4x
2026E
EV/Cash EBITDA
Median
29.0x
2025E
25.5x
2026E
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2.3 - Precedent M&A Transactions & Implied Enterprise Values for the Small-Molecule Pharmaceutical Manufacturing Companies secto

Selected M&A transactions

Date Target Description Buyer(s) Relevance EV EV/Revenue EV/EBITDA
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3. Potential Strategic Acquirers for Small-Molecule Pharmaceutical Manufacturing Companies

3.1 Top Strategic Buyers in Small-Molecule Pharmaceutical Manufacturing Companies

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3.2 - Strategic Buyer Groups & Adjacent Industry and Verticals to the Small-Molecule Pharmaceutical Manufacturing Companies sector

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Buyer group 1: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 2: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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Buyer group 3: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ

●● companies
Description: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
Key Products: β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ, β–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆβ–ˆ
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4. Financial Sponsors & Private Equity in Small-Molecule Pharmaceutical Manufacturing Companies

4.1 - Buyout Funds active in Small-Molecule Pharmaceutical Manufacturing Companies

Buyout Funds investing in Small-Molecule Pharmaceutical Manufacturing Companies companies

50+ funds
Description: Buyout funds focused on Small-Molecule Pharmaceutical Manufacturing Companies companies globally.

4.2 - 4.2 - Growth Capital & Late-Stage Investorsin Small-Molecule Pharmaceutical Manufacturing Companies sector

Growth Equity Funds in Small-Molecule Pharmaceutical Manufacturing Companies companies

40+ funds
Description: Growth equity funds focused on Small-Molecule Pharmaceutical Manufacturing Companies companies globally.
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Valuation FAQ: Small-Molecule Pharmaceutical Manufacturing Companies

What is the current median EV/Revenue multiple for Small-Molecule Pharmaceutical Manufacturing Companies?

Based on our index of public trading comparables, the median Enterprise Value to Revenue (EV/Rev) multiple for the Small-Molecule Pharmaceutical Manufacturing Companies sector is currently ●.●x. High-growth peers in the top quartile are trading at ●●.●x. View full data.

What is the average EV/EBITDA multiple for companies in this sector?

Profitable companies in the Small-Molecule Pharmaceutical Manufacturing Companies sector trade at a median EV/EBITDA multiple of ●●.●x. This represents a change vs the 5-year historical average. Our platform tracks EBITDA multiples for Small-Molecule Pharmaceutical Manufacturing Companies and other key peer groups.

How have valuation multiples for Small-Molecule Pharmaceutical Manufacturing Companies trended over the last 5 years?

Valuations have adjusted since 2021. The sector saw peak multiples of ●●.●x EV/Revenue, settling to a 5-year average of ●.●x today. Access our Historical Trends chart for granular monthly data.

What are recent M&A transaction multiples in the Small-Molecule Pharmaceutical Manufacturing Companies space?

Recent precedent transactions indicate implied enterprise values ranging from ●.●x to ●●.●x Revenue. Private market deals often trade at a liquidity discount compared to public peers. Unlock the full list of precedent transactions.

Which public companies are used as trading comps for Small-Molecule Pharmaceutical Manufacturing Companies?

The primary trading comparable group includes Small-Molecule Pharmaceutical Manufacturing Companies. Key constituents used for benchmarking include large-cap leaders and specialized mid-cap players. See the full list of companies in the Public Trading Comps section.

How do I value a private company in the Small-Molecule Pharmaceutical Manufacturing Companies sector?

Valuing a private Small-Molecule Pharmaceutical Manufacturing Companies company typically involves applying current EV/Revenue and EV/EBITDA multiples from public peers to the private company's financial metrics. A discount for lack of marketability (DLOM) of 20-30% is often applied. Our private company valuation database provides the exact multiples needed for this calculation.

What are the Small-Molecule Pharmaceutical Manufacturing Companies industry valuation multiples for 2025?

For 2025, the Small-Molecule Pharmaceutical Manufacturing Companies industry is trading at a median EV/Revenue multiple of ●.●x. This reflects current market sentiment, interest rates, and growth expectations. Access our platform to see how these multiples have changed from 2024 to 2025.

What is the difference between trading comps and transaction multiples for Small-Molecule Pharmaceutical Manufacturing Companies?

Trading comps look at how public markets value similar companies today, while transaction multiples (or precedent transactions) look at the price paid in past M&A deals. Transaction multiples often include a "control premium," typically resulting in higher valuations than trading comps. Our database tracks both trading multiples and M&A transaction multiples.

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